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IRIS è il sistema di gestione integrata dei dati della ricerca (persone, progetti, pubblicazioni, attività) adottato dall'Università degli Studi di Milano.
AIR nasce in UNIMI nel 2006 con lo scopo di raccogliere, documentare e conservare le informazioni sulla produzione scientifica dell'Università degli Studi di Milano e costituisce di fatto l'Anagrafe della ricerca dell'Ateneo.
EnglishPurpose: To verify whether stress-induced transient ischemic dilation (TID) of the left ventricle may help refine prognostic assessment of patients with resting systolic dysfunction and fixed perfusion defects. Methods: Two hundred seventy patients with resting ejection fraction ≤50% and fixed perfusion defects on exercise (n=180) or dipyridamole (n=90) ECG-gated single-photon emission computed tomography (SPECT) were followed-up for the combined endpoint of death, acute coronary syndrome, and clinically-driven revascularization. The TID ratio was defined as the ratio of LV volumes at stress and rest. Results: During a median time of 24 months, 47 events (10 deaths, 20 acute coronary syndromes and 17 revascularization) were observed. After adjusting for clinical and stress testing variables, the unfeasible exercise test [hazard ratio (HR) 1.82, 95% confidence interval (CI) 1.02, 3.24] and the highest quartile of TID ratio [HR 1.93, 95% CI 1.05, 3.54] were the only independent predictors of outcome. The highest quartile of TID ratio was associated to significantly lower percent of event-free survival. Conclusions: Left ventricular TID ratio helps refine outcome prediction in patients with resting systolic dysfunction and fixed perfusion defects, thus reducing risk of a false negative result.
Prognostic implications of stress-induced transient ischemic dilation of the left ventricle in patients with systolic dysfunction and fixed perfusion defects / A. Bestetti, R. Bigi, P. Terranova, F. Lombardi, C. Fiorentini. - In: INTERNATIONAL JOURNAL OF CARDIOLOGY. - ISSN 0167-5273. - 140:3(2010 Apr 30), pp. 323-327.
| Titolo: | Prognostic implications of stress-induced transient ischemic dilation of the left ventricle in patients with systolic dysfunction and fixed perfusion defects |
| Autori: | |
| Settore Scientifico Disciplinare: | Settore MED/36 - Diagnostica per Immagini e Radioterapia |
| Data di pubblicazione: | 30-apr-2010 |
| Rivista: | |
| Tipologia: | Article (author) |
| Digital Object Identifier (DOI): | http://dx.doi.org/10.1016/j.ijcard.2008.11.121 |
| Appare nelle tipologie: | 01 - Articolo su periodico |
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