Background: Increased cancer rates have been documented in people residing in areas around Naples characterized by illegal dumping and incineration of waste. Hypothesis: Risk of cancer in dogs and cats is associated with waste management. Animals: Four hundred and fifty-three dogs and cats with cancer and 1,554 cancer-free animals. Methods: Hospital-based case-control study in Naples (low danger) and nearby cities having a history of illegal waste dumping (high danger). Odds ratio (OR) between high-and low-danger areas was calculated for all tumors and various malignancies in dogs and cats. Results: An increased risk for cancer development was identified in dogs but not in cats residing in high-danger areas (OR: 1.55; 95% confidence interval: 1.18-2.03; P<.01). A 2.39-fold increased risk of lymphoma (P<.01) accounted for the greater tumor frequency in dogs residing in high-danger areas. The risk of mast cell tumor and mammary cancer did not differ in dogs residing in high- or low-danger areas. Conclusions and Clinical Importance: Waste emission from illegal dumping sites increases cancer risk in dogs residing in high-danger areas. An increased prevalence of lymphoma has been previously recognized in humans living close to illegal waste dumps. Thus, epidemiological studies of spontaneous tumors in dogs might suggest a role for environmental factors in canine and human carcinogenesis and can predict health hazards for humans.
Association between Waste Management and Cancer in Companion Animals / L. Marconato, C. Leo, R. Girelli, S. Salvi, F. Abramo, G. Bettini, S. Comazzi, P. Nardi, F. Albanese, E. Zini. - In: JOURNAL OF VETERINARY INTERNAL MEDICINE. - ISSN 0891-6640. - 23:3(2009 May), pp. 564-569.
|Titolo:||Association between Waste Management and Cancer in Companion Animals|
|Parole Chiave:||Carcinogenicity; Cat; Dioxin; Dog; Epidemiology; Lymphoma|
|Settore Scientifico Disciplinare:||Settore VET/03 - Patologia Generale e Anatomia Patologica Veterinaria|
Settore VET/08 - Clinica Medica Veterinaria
|Data di pubblicazione:||mag-2009|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1111/j.1939-1676.2009.0278.x|
|Appare nelle tipologie:||01 - Articolo su periodico|