We compared the laboratory and clinical findings of 179 patients with essential thrombocythemia (ET) and 77 with polycythemia vera (PV) classified according to the presence of the JAK2 V617F mutation. A gradient between patients with JAK2 wild-type ET, JAK2 V617F ET and PV (all carrying the JAK2 mutation) was observed. The rate of thrombotic complications in JAK2-positive ET was significantly higher than in wild-type ET and not statistically different from that of PV patients.
Low risk IgG Monoclonal Gammopathy of undetermined significance (MGUS) : proposal and validation of a prognostic scoring system / F.G. Rossi, L. Marcheselli, D. Rossi, V. Callea, A. Guffanti, V. Federico, M. De Muro, A. Baraldi, P. Musto, A. Bacigalupo, G. Gaidano, M.T. Petrucci, M. Goldaniga, L. De Paoli, L. Baldini. - In: HAEMATOLOGICA. - ISSN 0390-6078. - 92:Suppl. 3(2007 Oct), pp. 135-135. ((Intervento presentato al 41. convegno Congress of the Italian Society of Hematology tenutosi a Bologna nel 2007.
Low risk IgG Monoclonal Gammopathy of undetermined significance (MGUS) : proposal and validation of a prognostic scoring system
F.G. RossiPrimo
;L. BaldiniUltimo
2007
Abstract
We compared the laboratory and clinical findings of 179 patients with essential thrombocythemia (ET) and 77 with polycythemia vera (PV) classified according to the presence of the JAK2 V617F mutation. A gradient between patients with JAK2 wild-type ET, JAK2 V617F ET and PV (all carrying the JAK2 mutation) was observed. The rate of thrombotic complications in JAK2-positive ET was significantly higher than in wild-type ET and not statistically different from that of PV patients.
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