Despite significant advances in intraoperative antimicrobial procedures, deep infection remains the most devastating complication following total joint arthroplasty. Clinical studies'' results and safety profile of antibiotic-loaded bone cement are discussed in this review. Antibiotic bone cement prophylaxis is a safe and effective strategy in reducing the risk of deep infection following primary total joint arthroplasty.
Prophylactic use of antibiotic-loaded bone cement in primary total knee replacement / P. Randelli, F.R. Evola, P. Cabitza, L. Polli, M. Denti, L. Vaienti. - In: KNEE SURGERY, SPORTS TRAUMATOLOGY, ARTHROSCOPY. - ISSN 0942-2056. - 18:2(2010 Feb), pp. 181-186. [10.1007/s00167-009-0921-y]
Prophylactic use of antibiotic-loaded bone cement in primary total knee replacement
P. RandelliPrimo
;P. Cabitza;L. VaientiUltimo
2010
Abstract
Despite significant advances in intraoperative antimicrobial procedures, deep infection remains the most devastating complication following total joint arthroplasty. Clinical studies'' results and safety profile of antibiotic-loaded bone cement are discussed in this review. Antibiotic bone cement prophylaxis is a safe and effective strategy in reducing the risk of deep infection following primary total joint arthroplasty.
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