Refined Shrimp Peptide Concentrate: Regulatory, Value Chain and Circular Blue Bioeconomy Perspectives

The European Union Regulation (EU) 2015/2283 on novel foods has created new oppor- tunities for the valorization of marine by-products within the framework of the circular bioeconomy and sustainable blue economy. Refined shrimp peptide concentrate (RSPC), obtained through enzymatic hydrolysis of Pandalus borealis shells and heads, represents a relevant case study for examining the interaction between food innovation, regulatory assessment, sustainability, and value-chain development. This study analyzes the EFSA scientific opinion on RSPC and reviews available compositional, toxicological, allergenicity, and clinical evidence, contextualizing the ingredient within European policies on circular economy, resource efficiency, and sustainable food systems. The assessment indicates that RSPC consists mainly of 8 low-molecular-weight peptides with demonstrated angiotensin- converting enzyme (ACE) inhibitory activity and potential applications in blood pressure management. Beyond its functional properties, the valorization of shrimp processing by- products offers opportunities to reduce waste generation, increase resource efficiency, and create new economic value within the seafood sector. The case study highlights how the novel food regulatory framework can support the safe market introduction of innovative marine-derived ingredients while contributing to circular economy objectives. Although challenges related to allergenicity management, consumer acceptance, and industrial scala- bility remain, RSPC demonstrates the potential of marine by-product valorization to foster more sustainable, resilient, and economically viable food systems.