Disclosed is a process for preparing di-, tri-, or tetrasaccharides useful as intermediates for the synthesis of vaccine adjuvants. The process comprises reacting in the presence of a dehydrating agent and a sugar catalyst characterized by hydroxy groups converted to trichloroacetimidate or N-phenyl trifluoroacetimidate.
Process for preparing Di-, Tri-, or tetra-saccharides / S. Schivardi, L. Senaldi, A. Bernardi, P. Allegrini, A. Bonetti, A. Gambini, F. Peterlongo.
Process for preparing Di-, Tri-, or tetra-saccharides
S. Schivardi;L. Senaldi;A. Bernardi;
2026
Abstract
Disclosed is a process for preparing di-, tri-, or tetrasaccharides useful as intermediates for the synthesis of vaccine adjuvants. The process comprises reacting in the presence of a dehydrating agent and a sugar catalyst characterized by hydroxy groups converted to trichloroacetimidate or N-phenyl trifluoroacetimidate.
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