Introduction: Bronchoscopic lung volume reduction (BLVR) with endobronchial valves (EBVs) is an effective and minimally invasive alternative to lung volume reduction surgery for some patients with severe emphysema. While generally well tolerated, it may lead to rare but serious complications. Pulmonary lobar torsion and secondary infarction are known postoperative complications after thoracic surgery but have not been previously reported following BLVR. Case Presentation: A 70-year-old woman with chronic obstructive pulmonary disease underwent EBV placement in the right upper lobe, with a good lung function and clinical improvement. Fifteen months after placement, she presented with epigastric pain, hemoptysis, and respiratory distress. Imaging revealed a torsion of the right upper lobe, initially misinterpreted as pneumonia, which necessitated an urgent thoracotomy and lobectomy. Intraoperative and histopathological findings were compatible with the diagnosis of lobar torsion with ischemic necrosis. Conclusion: This case presents the first reported pulmonary lobar torsion following EBV treatment. The clinical presentation can be nonspecific or with misleading symptoms, potentially leading to diagnostic delays. Clinicians should be aware of such complication in patients with previous BLVR presenting with new or unexplained clinical findings. Imaging and early surgical intervention are critical to prevent life-threatening complications.

Pulmonary Lobar Torsion following Bronchoscopic Lung Volume Reduction with Endobronchial Valves: A Case Report / M. Brancaleone, B.C.. - In: RESPIRATION. - ISSN 0025-7931. - (2026). [Epub ahead of print] [10.1159/000550582]

Pulmonary Lobar Torsion following Bronchoscopic Lung Volume Reduction with Endobronchial Valves: A Case Report

B. Cavazzutti
Secondo
;
F. Di Marco;
2026

Abstract

Introduction: Bronchoscopic lung volume reduction (BLVR) with endobronchial valves (EBVs) is an effective and minimally invasive alternative to lung volume reduction surgery for some patients with severe emphysema. While generally well tolerated, it may lead to rare but serious complications. Pulmonary lobar torsion and secondary infarction are known postoperative complications after thoracic surgery but have not been previously reported following BLVR. Case Presentation: A 70-year-old woman with chronic obstructive pulmonary disease underwent EBV placement in the right upper lobe, with a good lung function and clinical improvement. Fifteen months after placement, she presented with epigastric pain, hemoptysis, and respiratory distress. Imaging revealed a torsion of the right upper lobe, initially misinterpreted as pneumonia, which necessitated an urgent thoracotomy and lobectomy. Intraoperative and histopathological findings were compatible with the diagnosis of lobar torsion with ischemic necrosis. Conclusion: This case presents the first reported pulmonary lobar torsion following EBV treatment. The clinical presentation can be nonspecific or with misleading symptoms, potentially leading to diagnostic delays. Clinicians should be aware of such complication in patients with previous BLVR presenting with new or unexplained clinical findings. Imaging and early surgical intervention are critical to prevent life-threatening complications.
Bronchoscopic lung volume reduction; Case report; Endobronchial valves; Lobar torsion; Lobectomy
Settore MEDS-07/A - Malattie dell'apparato respiratorio
2026
23-gen-2026
Article (author)
File in questo prodotto:
File Dimensione Formato  
CasereportBLVR_version25-09.pdf

accesso riservato

Tipologia: Post-print, accepted manuscript ecc. (versione accettata dall'editore)
Licenza: Nessuna licenza
Dimensione 1.26 MB
Formato Adobe PDF
1.26 MB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/1248744
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 0
  • ???jsp.display-item.citation.isi??? ND
  • OpenAlex 0
social impact