Advances in cancer biology and drug development now enable treatments tailored to individual tumor profile. Targeting specific molecular alterations marked a significant step forward in cancer care, including breast cancer. Access to these therapies is improving thanks to the implementation of molecular tumor boards and efforts to provide molecular diagnostics at sustainable costs for all. In this context, we highlight recent progress in breast cancer therapy, focusing on biomarker-driven approaches, immunotherapy, and precision medicine paving the way for increasingly personalized and effective options.

Advancing breast cancer therapy in the era of molecular diagnostics / M.G. Carnevale, R.R. Colciago, M.C. De Santis, L. Cortesi, C. De Marco, A. Marra, A. Vingiani, F. Nolè, G. Curigliano, G. Pruneri, A. Llombart-Cussac, S. Di Cosimo, J. Cortes. - In: BREAST. - ISSN 1532-3080. - 82:(2025 Aug), pp. 104488.1-104488.11. [10.1016/j.breast.2025.104488]

Advancing breast cancer therapy in the era of molecular diagnostics

A. Marra;A. Vingiani;G. Curigliano;G. Pruneri;
2025

Abstract

Advances in cancer biology and drug development now enable treatments tailored to individual tumor profile. Targeting specific molecular alterations marked a significant step forward in cancer care, including breast cancer. Access to these therapies is improving thanks to the implementation of molecular tumor boards and efforts to provide molecular diagnostics at sustainable costs for all. In this context, we highlight recent progress in breast cancer therapy, focusing on biomarker-driven approaches, immunotherapy, and precision medicine paving the way for increasingly personalized and effective options.
Biomarkers; Breast cancer; Molecularly-informed therapy; Mutations; Precision medicine; Targeted therapy
Settore MEDS-09/A - Oncologia medica
ago-2025
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/1247552
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