Gestione del paziente con stenosi valvolare aortica e concomitante insufficienza mitralica: sfide diagnostiche e strategie terapeutiche nell’era dell’interventistica strutturale

Severe aortic stenosis and mitral regurgitation frequently coexist and pose significant diagnostic and therapeutic challenges. The hemodynamic interplay between these two valvular diseases can obscure the accurate assessment of each lesion, necessitating an advanced understanding of flow dynamics and cardiac remodeling. This review explores the complex relationship between aortic stenosis and mitral regurgitation, highlighting pathophysiological mechanisms, diagnostic pitfalls, and contemporary management strategies. By synthesizing current evidence, we aim to provide clinicians with practical insights to guide decision-making in the era of advanced cardiac imaging and percutaneous interventions.