Melanoma is one of the most aggressive forms of skin cancer, necessitating advanced diagnostic tools to improve early detection. This study presents a novel AI-driven approach that combines deep neural networks with quantum computing techniques for enhanced lesion classification. Specifically, we employ a U-Net model for segmentation and a hybrid Convolutional Neural Network - Quantum Neural Network (CNN-QNN) for classification. Our approach achieves a precision of 99.67 %, recall of 99.67 %, and an overall accuracy of 99.35 % on the HAM10000 dataset. Additionally, we report a sensitivity of 99.4 %, a specificity of 99.2 %, and a macro F1-score of 99.5 %, significantly surpassing traditional CNN-based classifiers. This hybrid model outperforms conventional deep learning approaches, demonstrating its potential for aiding dermatologists in clinical decision-making. A comparative analysis with state-of-the-art models further validates the effectiveness of our method.

Optimizing melanoma diagnosis: A hybrid deep learning and quantum computing approach for enhanced lesion classification / M. Frasca, I. Cutica, G. Pravettoni, D. La Torre. - In: INTELLIGENCE-BASED MEDICINE. - ISSN 2666-5212. - 12:(2025 Jun), pp. 100264.1-100264.12. [10.1016/j.ibmed.2025.100264]

Optimizing melanoma diagnosis: A hybrid deep learning and quantum computing approach for enhanced lesion classification

M. Frasca
Primo
;
I. Cutica;G. Pravettoni;D. La Torre
Ultimo
2025

Abstract

Melanoma is one of the most aggressive forms of skin cancer, necessitating advanced diagnostic tools to improve early detection. This study presents a novel AI-driven approach that combines deep neural networks with quantum computing techniques for enhanced lesion classification. Specifically, we employ a U-Net model for segmentation and a hybrid Convolutional Neural Network - Quantum Neural Network (CNN-QNN) for classification. Our approach achieves a precision of 99.67 %, recall of 99.67 %, and an overall accuracy of 99.35 % on the HAM10000 dataset. Additionally, we report a sensitivity of 99.4 %, a specificity of 99.2 %, and a macro F1-score of 99.5 %, significantly surpassing traditional CNN-based classifiers. This hybrid model outperforms conventional deep learning approaches, demonstrating its potential for aiding dermatologists in clinical decision-making. A comparative analysis with state-of-the-art models further validates the effectiveness of our method.
Artificial intelligence; Dermatoscopic images; Medical imaging; Melanoma; Quantum neural network
Settore INFO-01/A - Informatica
giu-2025
Article (author)
File in questo prodotto:
File Dimensione Formato  
1-s2.0-S2666521225000687-main.pdf

accesso aperto

Tipologia: Publisher's version/PDF
Licenza: Creative commons
Dimensione 2.76 MB
Formato Adobe PDF
2.76 MB Adobe PDF Visualizza/Apri
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/1244142
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
  • OpenAlex 0
social impact