The present invention relates to the use of inhibitors of the histone deacetylases for the preparation of a medicament for the treatment of pathologies caused by increased levels of plasma cholesterol and plasma and hepatic triglycerides. Particularly, the invention relates to the use of said inhibitors for the preparation of a medicament for the treatment of diseases such as hyperlipidaemia, particularly, hypercholesterolaemia, hypertriglyceridaemia, atherosclerosis, cardiovascular and cerebrovascular pathologies, obesity, diabetes metabolic syndromes.
Inhibition of histone deacetylases for the treatment of hyperlipidemias and prevention of atherosclerosis and cardiovascular diseases / M. Crestani, C. Godio, N. Mitro.
Inhibition of histone deacetylases for the treatment of hyperlipidemias and prevention of atherosclerosis and cardiovascular diseases
M. CrestaniPrimo
;C. GodioSecondo
;N. MitroUltimo
2005
Abstract
The present invention relates to the use of inhibitors of the histone deacetylases for the preparation of a medicament for the treatment of pathologies caused by increased levels of plasma cholesterol and plasma and hepatic triglycerides. Particularly, the invention relates to the use of said inhibitors for the preparation of a medicament for the treatment of diseases such as hyperlipidaemia, particularly, hypercholesterolaemia, hypertriglyceridaemia, atherosclerosis, cardiovascular and cerebrovascular pathologies, obesity, diabetes metabolic syndromes.
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