We analyzed mutations in the 5′ non-coding region of the BCL-6 gene in 46 cases of primary cutaneous B-cell lymphomas (PCBCL), using a polymerase chain reaction single strand conformation polymorphism (PCR-SSCP) method. The results indicate that PCBCL display a low frequency of mutations and support a marginal zone B-cell origin for most of these neoplasms.

BCL-6 gene mutations in primary cutaneous B-cell lymphomas / U. Gianelli, A. Cerri, B. Cassani, L. Moneghini, P.R. Raviele, E. Berti, S. Bosari. - In: HAEMATOLOGICA. - ISSN 0390-6078. - 89:5(2004), pp. 624-626.

BCL-6 gene mutations in primary cutaneous B-cell lymphomas

U. Gianelli;A. Cerri;E. Berti;S. Bosari
2004

Abstract

We analyzed mutations in the 5′ non-coding region of the BCL-6 gene in 46 cases of primary cutaneous B-cell lymphomas (PCBCL), using a polymerase chain reaction single strand conformation polymorphism (PCR-SSCP) method. The results indicate that PCBCL display a low frequency of mutations and support a marginal zone B-cell origin for most of these neoplasms.
BCL-6 gene; BCL-6 mutations; Cutaneous lymphoma; Extranodal non-Hodgkin's lymphoma; Primary cutaneous B-cell lymphomas
Settore MED/35 - Malattie Cutanee e Veneree
Settore MED/08 - Anatomia Patologica
2004
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/12393
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