The chromatographic purification on silica gel of complex mixtures can pose several issues for chemists (e.g. degradation or racemization). Switching to aluminium oxide as the stationary phase could be a strategically successful choice. Herein, some practical advice for its effective use is disclosed.
Practical use of aluminium oxide in chromatographic purifications =Uso práctico del óxido de aluminio en purificaciones cromatográficas / V. Pace, M. Miele, E.I. Comas Iwasita, L. Castoldi. - In: ANALES DE LA REAL ACADEMIA NACIONAL DE FARMACIA. - ISSN 1697-4271. - 91:4(2026), pp. 393-393. [10.53519/analesranf.2025.91.04.06]
Practical use of aluminium oxide in chromatographic purifications =Uso práctico del óxido de aluminio en purificaciones cromatográficas
L. Castoldi
Ultimo
2026
Abstract
The chromatographic purification on silica gel of complex mixtures can pose several issues for chemists (e.g. degradation or racemization). Switching to aluminium oxide as the stationary phase could be a strategically successful choice. Herein, some practical advice for its effective use is disclosed.
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