α-Fluoromethyl amides were prepared through the chemoselective nucleophilic addition of fluoromethyl-lithium to isocyanates.
Chemoselective synthesis of α-fluoromethyl amides via the controlled addition of LiCH2F to N-aryl and N-alkyl isocyanates / D. Castiglione, A. Nardi, M. Miele, L. Castoldi, V. Pace. - In: CHEMICAL COMMUNICATIONS. - ISSN 1359-7345. - 62:22(2026), pp. 6155-6159. [10.1039/d5cc06730h]
Chemoselective synthesis of α-fluoromethyl amides via the controlled addition of LiCH2F to N-aryl and N-alkyl isocyanates
L. Castoldi
Penultimo
;
2026
Abstract
α-Fluoromethyl amides were prepared through the chemoselective nucleophilic addition of fluoromethyl-lithium to isocyanates.
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