Lysine Cyclodeaminase (LCD) predominantly catalyzes the biosynthesis of piperidine derivatives using NAD+ as cofactor and exhibits strict substrate size specificity, catalyzing only substrates no larger than L-lysine.
Mechanistic Insights into Lysine Cyclodeaminase Catalysis / Y. Wei, U. Guerrini, I. Eberini. 12. CECAM Virtual Winter School on Computational Chemistry : 26-30 January online 2026.
Mechanistic Insights into Lysine Cyclodeaminase Catalysis
Y. Wei;U. Guerrini;I. Eberini
2026
Abstract
Lysine Cyclodeaminase (LCD) predominantly catalyzes the biosynthesis of piperidine derivatives using NAD+ as cofactor and exhibits strict substrate size specificity, catalyzing only substrates no larger than L-lysine.
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