Idiopathic polyhydramnios is clinically linked to stillbirth; however, its placental histopathology remains poorly characterized. This is the first study analyzing placentas from stillbirths with idiopathic polyhydramnios, revealing frequent lesions of fetal and maternal vascular malperfusion. Findings support a previously unrecognized role of placental dysfunction in fetal compromise.
Hidden placental damage in stillbirths with idiopathic polyhydramnios / L. Avagliano, M. Benuzzi, F. Monari, G. Bulfamante. - In: EARLY HUMAN DEVELOPMENT. - ISSN 0378-3782. - 211:(2025 Dec), pp. 106393.1-106393.7. [10.1016/j.earlhumdev.2025.106393]
Hidden placental damage in stillbirths with idiopathic polyhydramnios
L. Avagliano
Primo
;G. BulfamanteUltimo
2025
Abstract
Idiopathic polyhydramnios is clinically linked to stillbirth; however, its placental histopathology remains poorly characterized. This is the first study analyzing placentas from stillbirths with idiopathic polyhydramnios, revealing frequent lesions of fetal and maternal vascular malperfusion. Findings support a previously unrecognized role of placental dysfunction in fetal compromise.
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