Gallbladder cancer (GBC) is a rare disease with a poor prognosis. Simple cholecystectomy may be an adequate treatment only for very early disease (Tis, T1a), whereas reoperation is recommended for more advanced disease (T1b and T2). Radical cholecystectomy should have two fundamental objectives: To radically resect the liver parenchyma and to achieve adequate clearance of the lymph nodes. However, recent studies have shown that compared with lymph node dissection alone, liver resection does not improve survival outcomes. The oncological roles of lymphadenectomy and liver resection is distinct. Therefore, for patients with incidental GBC without liver invasion, hepatic resection is not always mandatory.

Radical cholecystectomy without liver resection for peritoneal side early incidental gallbladder cancer / G. Piccolo, M. Barabino, G.N. Piozzi, P.P. Bianchi. - In: WORLD JOURNAL OF GASTROENTEROLOGY. - ISSN 2219-2840. - 30:32(2024 Aug 28), pp. 3739-3742. [10.3748/wjg.v30.i32.3739]

Radical cholecystectomy without liver resection for peritoneal side early incidental gallbladder cancer

P.P. Bianchi
Ultimo
2024

Abstract

Gallbladder cancer (GBC) is a rare disease with a poor prognosis. Simple cholecystectomy may be an adequate treatment only for very early disease (Tis, T1a), whereas reoperation is recommended for more advanced disease (T1b and T2). Radical cholecystectomy should have two fundamental objectives: To radically resect the liver parenchyma and to achieve adequate clearance of the lymph nodes. However, recent studies have shown that compared with lymph node dissection alone, liver resection does not improve survival outcomes. The oncological roles of lymphadenectomy and liver resection is distinct. Therefore, for patients with incidental GBC without liver invasion, hepatic resection is not always mandatory.
Early stage; Incidental gallbladder cancer; Liver resection; Radical cholecystectomy; Reoperation
Settore MEDS-06/A - Chirurgia generale
28-ago-2024
28-ago-2024
Article (author)
File in questo prodotto:
File Dimensione Formato  
WJG-30-3739.pdf

accesso aperto

Tipologia: Publisher's version/PDF
Licenza: Creative commons
Dimensione 344.89 kB
Formato Adobe PDF
344.89 kB Adobe PDF Visualizza/Apri
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/1205120
Citazioni
  • ???jsp.display-item.citation.pmc??? 2
  • Scopus 3
  • ???jsp.display-item.citation.isi??? ND
  • OpenAlex 7
social impact