Calprotectin is a S-100 family calcium- and zinc-binding protein. It derives predominantly from neutrophils and monocytes and it is detectable in body fluids and tissue samples. Fecal calprotectin is a marker of intestinal inflammation and it seems to be useful, in gastroenterological practice, for diagnosing and monitoring organic inflammatory bowel disorders (ulcerative colitis and Crohn’s disease) in adults and children. The aim of this review is to discuss biochemical, analytical and clinical findings of this promising marker of intestinal inflammation.
Calprotectina fecale : un nuovo indicatore di malattia infiammatoria intestinale / C. Merlotti, A. Dolci, L. Scapellato, M. Panteghini. - In: BIOCHIMICA CLINICA. - ISSN 0393-0564. - 29:5/6(2005), pp. 507-514.
Calprotectina fecale : un nuovo indicatore di malattia infiammatoria intestinale
A. Dolci;M. PanteghiniUltimo
2005
Abstract
Calprotectin is a S-100 family calcium- and zinc-binding protein. It derives predominantly from neutrophils and monocytes and it is detectable in body fluids and tissue samples. Fecal calprotectin is a marker of intestinal inflammation and it seems to be useful, in gastroenterological practice, for diagnosing and monitoring organic inflammatory bowel disorders (ulcerative colitis and Crohn’s disease) in adults and children. The aim of this review is to discuss biochemical, analytical and clinical findings of this promising marker of intestinal inflammation.
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