Necrotizing enterocolitis (NEC) is a typical disorder of preterm newborns, with a high mortality and morbidity rate. The therapeutic and nutritional management of disease depends on several factors. Its prognosis is linked, in addition to the severity of the disease and the need for surgery, to a correct enteral feeding in these patients. This study aims to identify the clinical characteristics of 18 patients with NEC, evaluating the different therapeutic paths undertaken, the type of formula used and the survival rate of this population. Average time of enteral nutrition before the NEC onset was 11,3 ± 11,6 days, with an average fasting period since the onset of 24 ± 18.9 days. 77.8% of patients received surgery and resumed enteral nutrition 17.7 ± 17.9 days after the intervention. The overall survival rate of our cohort was 55.5%. More prospective studies are needed to evaluate the long-term outcomes of survived children with NEC.

Necrotizing enterocolitis in the preterm: newborns medical and nutritional Management in a Single-Center Study / G. Savarino, M. Carta, M. Cimador, A. Corsello, M. Giuffre, I.A.M. Schierz, G. Serra, G. Corsello. - In: THE ITALIAN JOURNAL OF PEDIATRICS. - ISSN 1720-8424. - 47:1(2021), pp. 226.1-226.9. [10.1186/s13052-021-01180-8]

Necrotizing enterocolitis in the preterm: newborns medical and nutritional Management in a Single-Center Study

A. Corsello;G. Serra;
2021

Abstract

Necrotizing enterocolitis (NEC) is a typical disorder of preterm newborns, with a high mortality and morbidity rate. The therapeutic and nutritional management of disease depends on several factors. Its prognosis is linked, in addition to the severity of the disease and the need for surgery, to a correct enteral feeding in these patients. This study aims to identify the clinical characteristics of 18 patients with NEC, evaluating the different therapeutic paths undertaken, the type of formula used and the survival rate of this population. Average time of enteral nutrition before the NEC onset was 11,3 ± 11,6 days, with an average fasting period since the onset of 24 ± 18.9 days. 77.8% of patients received surgery and resumed enteral nutrition 17.7 ± 17.9 days after the intervention. The overall survival rate of our cohort was 55.5%. More prospective studies are needed to evaluate the long-term outcomes of survived children with NEC.
Enteral formulas; NEC; Necrotizing enterocolitis; Neonatology; Pediatric gastroenterology; Pediatric nutrition; Pediatric surgery; Preterm newborns; Very low birth weight infants
Settore MEDS-20/A - Pediatria generale e specialistica
2021
14-nov-2021
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/1185081
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