This case report is focused on a patient (a 32-year-old previously healthy man) with a femoral bone tissue tumor. The case underscores the diagnostic complexity of Telangiectatic Osteosarcoma (TOS) with Aneurysmal Bone Cystic (ABC) lesion and the importance of maintaining special immunohistochemical markers for differential diagnosis between low-grade osteosarcoma, primary ABC, and suspected TOS, which is a true mimicker of ABC. On the other hand, this presentation describes some molecular rearrangements seen in ABC.
Molecular Morphology of Telangiectatic Osteosarcoma Associated With Сystic Content: A Case Report / D. Makaridze, A. Mariamidze, T. Gvianishvili, G. Ottaviani, L. Gogiashvili. - In: CUREUS. - ISSN 2168-8184. - 17:8(2025 Aug), pp. e89658.1-e89658.6. [10.7759/cureus.89658]
Molecular Morphology of Telangiectatic Osteosarcoma Associated With Сystic Content: A Case Report
G. OttavianiPenultimo
;
2025
Abstract
This case report is focused on a patient (a 32-year-old previously healthy man) with a femoral bone tissue tumor. The case underscores the diagnostic complexity of Telangiectatic Osteosarcoma (TOS) with Aneurysmal Bone Cystic (ABC) lesion and the importance of maintaining special immunohistochemical markers for differential diagnosis between low-grade osteosarcoma, primary ABC, and suspected TOS, which is a true mimicker of ABC. On the other hand, this presentation describes some molecular rearrangements seen in ABC.
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