In candidates for hepatectomy, different techniques to induce liver hypertrophy and modulate the future liver remnant are available. However, their use in specific clinical scenarios is highly heterogeneous and there is no consensus about minimal safety standards needed to incorporate these strategies into routine clinical practice. The aim of this position paper was to summarize newly available evidence in the field and compare medical practice among different hepatobiliary surgical units to evaluate the transformative potential of liver hypertrophy techniques in surgical oncology. This paper sets the stage for a future structured consensus on the application of liver hypertrophy techniques before hepatectomy.

Liver hypertrophy techniques: a position paper from the Italian Group of Regenerative and Occlusive Worldwide-used techniques of hepatic Hypertrophy (I GROWtoH) / M. Serenari, F. Ratti, M.A. Hilal, F. Ardito, G. Berardi, U. Boggi, A. Cappelli, M. Cescon, U. Cillo, A. Cucchetti, L. De Carlis, F. De Cobelli, F. Di Benedetto, G. Ercolani, G.M. Ettorre, M. Fedi, A. Ferrero, F. Giuliante, G.L. Grazi, E. Gringeri, S. Gruttadauria, F. Izzo, M. Maestri, P. Magistri, M. Massani, V. Mazzaferro, R. Memeo, F. Mocchegiani, C. Mosconi, D. Patrono, M. Ravaioli, F. Romano, G. Rompianesi, N. Russolillo, A. Ruzzenente, C. Sposito, R. Troisi, G. Vennarecci, L. Viganò, M. Vivarelli, G. Zanus, P.M. Baptista, K. Oldhafer, E. Schadde, L. Aldrighetti, E. Jovine. - In: UPDATES IN SURGERY. - ISSN 2038-131X. - (2025), pp. 1-17. [Epub ahead of print] [10.1007/s13304-025-02364-1]

Liver hypertrophy techniques: a position paper from the Italian Group of Regenerative and Occlusive Worldwide-used techniques of hepatic Hypertrophy (I GROWtoH)

V. Mazzaferro;C. Sposito;
2025

Abstract

In candidates for hepatectomy, different techniques to induce liver hypertrophy and modulate the future liver remnant are available. However, their use in specific clinical scenarios is highly heterogeneous and there is no consensus about minimal safety standards needed to incorporate these strategies into routine clinical practice. The aim of this position paper was to summarize newly available evidence in the field and compare medical practice among different hepatobiliary surgical units to evaluate the transformative potential of liver hypertrophy techniques in surgical oncology. This paper sets the stage for a future structured consensus on the application of liver hypertrophy techniques before hepatectomy.
Liver function; Liver hypertrophy; Liver volume; Portal vein embolization
Settore MEDS-06/A - Chirurgia generale
2025
26-ago-2025
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/1180695
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