People with HIV (PWH) with four-drug class resistance (4DR) had a higher risk of death than non-4DR PWH, primarily due to lower CD4 cell counts. The priority for this vulnerable population is achieving virological control to enable immune recovery.
All-Cause Mortality in People with Four-Class Drug-Resistant HIV: A Matched Cohort Analysis with Data from the PRESTIGIO Registry / A. Giacomelli, N. Capra, R. Lolatto, R. Gagliardini, T. Clemente, L. Calza, C. Torti, F. Lagi, C. Fornabaio, G. Marchetti, G. Orofino, V. Spagnuolo. - In: CLINICAL INFECTIOUS DISEASES. - ISSN 1058-4838. - (2025 Aug). [Epub ahead of print] [10.1093/cid/ciaf421]
All-Cause Mortality in People with Four-Class Drug-Resistant HIV: A Matched Cohort Analysis with Data from the PRESTIGIO Registry
A. Giacomelli
Primo
;G. Marchetti;
2025
Abstract
People with HIV (PWH) with four-drug class resistance (4DR) had a higher risk of death than non-4DR PWH, primarily due to lower CD4 cell counts. The priority for this vulnerable population is achieving virological control to enable immune recovery.
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