Altered metabolic function has many detrimental effects on the body that can manifest as cardiovascular and liver diseases. Traditional approaches to understanding and treating metabolic dysfunction-associated disorders have been organ-centered, leading to silo-type disease care. However, given the broad impact that systemic metabolic dysfunction has on the human body, approaches that simultaneously involve multiple medical specialists need to be developed and encouraged to optimize patient outcomes. In this review, we highlight how several of the treatments developed for cardiac care may have a beneficial effect on the liver and vice versa, suggesting that there is a need to target the disease process, rather than specifically target the cardiovascular or liver specific sequelae of metabolic dysfunction.

Metabolic dysfunction-associated steatotic liver disease: An opportunity for collaboration between cardiology and hepatology / P. Raggi, J. Milic, M. Manicardi, F. Cinque, M.G. Swain, G. Sebastiani, G. Guaraldi. - In: ATHEROSCLEROSIS. - ISSN 1879-1484. - 392:(2024 May), pp. 117523.1-117523.10. [10.1016/j.atherosclerosis.2024.117523]

Metabolic dysfunction-associated steatotic liver disease: An opportunity for collaboration between cardiology and hepatology

F. Cinque;
2024

Abstract

Altered metabolic function has many detrimental effects on the body that can manifest as cardiovascular and liver diseases. Traditional approaches to understanding and treating metabolic dysfunction-associated disorders have been organ-centered, leading to silo-type disease care. However, given the broad impact that systemic metabolic dysfunction has on the human body, approaches that simultaneously involve multiple medical specialists need to be developed and encouraged to optimize patient outcomes. In this review, we highlight how several of the treatments developed for cardiac care may have a beneficial effect on the liver and vice versa, suggesting that there is a need to target the disease process, rather than specifically target the cardiovascular or liver specific sequelae of metabolic dysfunction.
Diabetes mellitus; Fatty liver disease; Metabolic syndrome; Obesity; Steatohepatitis; Steatosis;
Settore MEDS-05/A - Medicina interna
mag-2024
16-mar-2024
Article (author)
File in questo prodotto:
File Dimensione Formato  
1-s2.0-S0021915024000832-main.pdf

accesso aperto

Tipologia: Publisher's version/PDF
Licenza: Creative commons
Dimensione 3.28 MB
Formato Adobe PDF
3.28 MB Adobe PDF Visualizza/Apri
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/1177090
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 6
  • ???jsp.display-item.citation.isi??? 6
  • OpenAlex 8
social impact