The present invention provides new glucide derivatives of formula (I) or (II) having a biological activity as inducers of erythroid cell differentiation, constituted by an acyl moiety linked to a 3-deoxyglucide unit through an amine group. The presence of a stable covalent bond between the acyl moiety and the 3-deoxyglucide moiety of the molecule enables rapid enzymatic hydrolysis of these derivatives to be avoided.

3-Deoxy-3-amide derivatives of carbohydrated as inducers of erythroid cell differentiation / G. Catelani, F. D'Andrea, R. Gambari, A. Spitaleri.

3-Deoxy-3-amide derivatives of carbohydrated as inducers of erythroid cell differentiation

A. Spitaleri
Methodology
2003

Abstract

The present invention provides new glucide derivatives of formula (I) or (II) having a biological activity as inducers of erythroid cell differentiation, constituted by an acyl moiety linked to a 3-deoxyglucide unit through an amine group. The presence of a stable covalent bond between the acyl moiety and the 3-deoxyglucide moiety of the molecule enables rapid enzymatic hydrolysis of these derivatives to be avoided.
Chiesi farmaceutici S.p.A.
Associazione veneta per la lotta alla Talassemia
Associazione per la lotta alla Talassemia di Ferrara
WO/2003/029263
PCT/IB2002/004042
TO2001A000922
10-apr-2003
Settore MEDS-09/B - Malattie del sangue
Settore CHEM-05/A - Chimica organica
https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2003029263
3-Deoxy-3-amide derivatives of carbohydrated as inducers of erythroid cell differentiation / G. Catelani, F. D'Andrea, R. Gambari, A. Spitaleri.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/1174997
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