This review highlights the most relevant and influential studies on coronary and structural cardiac computed tomography published in 2024. The clinical utility of coronary CT angiography (CCTA) continues to expand, supported by advancements in quantitative plaque analysis, functional assessment through FFR-CT, and the integration of artificial intelligence (AI). Photon-counting CT has emerged as a promising technology for improving image quality and diagnostic accuracy. In structural heart disease, CCT has become an indispensable tool for procedural planning and risk stratification across multiple valvular interventions. Moreover, CT-derived extracellular volume (CT-ECV) and AI-based assessment of myocardial mass and epicardial adipose tissue are gaining traction as novel prognostic biomarkers. These developments reflect the growing adoption of CCT in both clinical practice and cardiovascular research, underscoring its role as a cornerstone modality in modern cardiology.
Key advances in cardiac computed tomography: A review of the most relevant studies published in 2024 on coronary and structural heart disease / P.M. Rubio, H.M. Garcia-Garcia, A.A. Sanchez, A. Alfaddagh, D. Andreini, A. Baggiano, A. Canan, M. Chen, B.J.W. Chow, A. Chelliah, E. Conte, C.N. Dececco, T. Fairbairn, M. Ferencik, G. Feuchtner, B. Föellmer, C. Fuss, H. Gransar, A. Hamdan, B.K. Han, S. Jamieson, B. Ko, J.A. Leipsic, N. Madan, F. Michallek, S. Mushtaq, P. Nagpal, M. Ng, E. Nicol, H. Niinuma, G. Pontone, A. Pourmorteza, A. Reid, J.R. Weir-McCall, S. Whelton, M. Williams, J. Yu, A. Arbab-Zadeh. - In: JOURNAL OF CARDIOVASCULAR COMPUTED TOMOGRAPHY. - ISSN 1876-861X. - 19:3(2025 Jun), pp. 291-298. [10.1016/j.jcct.2025.04.008]
Key advances in cardiac computed tomography: A review of the most relevant studies published in 2024 on coronary and structural heart disease
D. Andreini;A. Baggiano;E. Conte;S. Mushtaq;G. Pontone;
2025
Abstract
This review highlights the most relevant and influential studies on coronary and structural cardiac computed tomography published in 2024. The clinical utility of coronary CT angiography (CCTA) continues to expand, supported by advancements in quantitative plaque analysis, functional assessment through FFR-CT, and the integration of artificial intelligence (AI). Photon-counting CT has emerged as a promising technology for improving image quality and diagnostic accuracy. In structural heart disease, CCT has become an indispensable tool for procedural planning and risk stratification across multiple valvular interventions. Moreover, CT-derived extracellular volume (CT-ECV) and AI-based assessment of myocardial mass and epicardial adipose tissue are gaining traction as novel prognostic biomarkers. These developments reflect the growing adoption of CCT in both clinical practice and cardiovascular research, underscoring its role as a cornerstone modality in modern cardiology.
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