Study Design Retrospective Cohort Study.Objectives To assess long-term alignment descriptors correlating with mechanical complications.Methods The study included adult spinal deformity cases older than 18, with a minimum of four instrumented levels and a 5-year follow-up. Exclusions: previous spinal fusion, neuromuscular/rheumatic diseases, active infections, tumors, or incomplete radiographic exams. Collected data: demographic, surgical, pre- and post-operative spinopelvic parameters, and post-operative complications. The GAP score, original Roussouly type restoration, Schwab's criteria, and Odontoid to hip axis angle were evaluated using machine learning and logistic regression. Complications were evaluated with a Kaplan-Meier curve.Results Two hundred and twelve patients fulfilled the inclusion and exclusion criteria and were enrolled in the study. The observed rate of revision surgery for mechanical complications was 40.6% (86 out of 212 patients). Higher post-operative GAP scores were associated with increased risks of revision for junctional failure (AUC = 0.72 [IC 95%] 0.62-0.80). The inability to restore the original Roussouly spinal shape was statistically associated with higher mechanical failure rates. A machine-learning approach and subsequent logistic regression found that the GAP score and original Roussouly type restoration are the most important predictors for mechanical failure, and GAP score lordosis distribution index and relative pelvic version are the most important factors to predict the risk of mechanical failure.Conclusions In our series, a proper post-operative GAP Score and the restoration of the original Roussouly type significantly minimize mechanical complication rates. We observed that junctional failure tends to occur earlier among complications, while implant failure occurs later in the follow-up.

How to reduce the risk of mechanical failures in adult deformity surgery: comparing GAP score and Roussouly type restoration / D. Compagnone, R. Cecchinato, A. Pezzi, F. Langella, M. Damilano, D. Vanni, A. Redaelli, C. Lamartina, P. Berjano. - In: GLOBAL SPINE JOURNAL. - ISSN 2192-5682. - (2025 Mar 20). [Epub ahead of print] [10.1177/21925682251328285]

How to reduce the risk of mechanical failures in adult deformity surgery: comparing GAP score and Roussouly type restoration

R. Cecchinato
Secondo
;
A. Pezzi;
2025

Abstract

Study Design Retrospective Cohort Study.Objectives To assess long-term alignment descriptors correlating with mechanical complications.Methods The study included adult spinal deformity cases older than 18, with a minimum of four instrumented levels and a 5-year follow-up. Exclusions: previous spinal fusion, neuromuscular/rheumatic diseases, active infections, tumors, or incomplete radiographic exams. Collected data: demographic, surgical, pre- and post-operative spinopelvic parameters, and post-operative complications. The GAP score, original Roussouly type restoration, Schwab's criteria, and Odontoid to hip axis angle were evaluated using machine learning and logistic regression. Complications were evaluated with a Kaplan-Meier curve.Results Two hundred and twelve patients fulfilled the inclusion and exclusion criteria and were enrolled in the study. The observed rate of revision surgery for mechanical complications was 40.6% (86 out of 212 patients). Higher post-operative GAP scores were associated with increased risks of revision for junctional failure (AUC = 0.72 [IC 95%] 0.62-0.80). The inability to restore the original Roussouly spinal shape was statistically associated with higher mechanical failure rates. A machine-learning approach and subsequent logistic regression found that the GAP score and original Roussouly type restoration are the most important predictors for mechanical failure, and GAP score lordosis distribution index and relative pelvic version are the most important factors to predict the risk of mechanical failure.Conclusions In our series, a proper post-operative GAP Score and the restoration of the original Roussouly type significantly minimize mechanical complication rates. We observed that junctional failure tends to occur earlier among complications, while implant failure occurs later in the follow-up.
adult spinal deformity; surgical complications; mechanical failures; GAP Score; Roussouly classification; 3 retrospective cohort study
Settore MEDS-19/A - Malattie dell'apparato locomotore
20-mar-2025
20-mar-2025
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/1156880
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