During stress, cells form large cytoplasmic mRNA-protein granules called stress granules and P-bodies. Wilbertz et al. quantified the colocalization and dynamics of mRNAs with stress granules and P-bodies. During recovery, granule localization during stress did not alter the translation or degradation of mRNAs compared to transcripts that remained in the cytosol.
Single-Molecule Imaging of mRNA Localization and Regulation during the Integrated Stress Response / J.H. Wilbertz, F. Voigt, I. Horvathova, G. Roth, Y. Zhan, J.A. Chao. - In: MOLECULAR CELL. - ISSN 1097-2765. - 73:5(2019 Mar), pp. 946-958, e1-e7. [10.1016/j.molcel.2018.12.006]
Single-Molecule Imaging of mRNA Localization and Regulation during the Integrated Stress Response
Y. Zhan;
2019
Abstract
During stress, cells form large cytoplasmic mRNA-protein granules called stress granules and P-bodies. Wilbertz et al. quantified the colocalization and dynamics of mRNAs with stress granules and P-bodies. During recovery, granule localization during stress did not alter the translation or degradation of mRNAs compared to transcripts that remained in the cytosol.
| File | Dimensione | Formato | |
|---|---|---|---|
|
1-s2.0-S1097276518310360-main.pdf
accesso riservato
Tipologia:
Publisher's version/PDF
Licenza:
Nessuna licenza
Dimensione
3.13 MB
Formato
Adobe PDF
|
3.13 MB | Adobe PDF | Visualizza/Apri Richiedi una copia |
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
