Efficacy of Septoplasty in Patients with Nasal Obstruction: A Systematic Review and Meta‐analysis

Objective: Septoplasty is the most frequently performed ENT surgery to correct nasal septal deviation (NSD). The present study aimed to quantify the effectiveness of septoplasty with or without turbinate surgery according to NOSE questionnaire scores, with the hypothesis that it is able to clinically improve patient-reported nasal obstructive symptoms in the post-operative follow-up. Methods: An electronic search was performed on PubMed/MEDLINE, Embase, and Cochrane Library. The primary outcome was the change in NOSE score at 6 months after surgery. It was assessed with the mean difference (MD) between baseline and postoperative results. Results: A total of 2577 patients (males: 65.1%, 95% CI: 59.9–70.2) with a mean age of 33.3 years (n = 1456, 95% CI: 30.4–36.2) were included in this meta-analysis. The pooled baseline NOSE mean score was 68.1 (n = 2577, 95% CI: 64.3–71.9). The pooled MD in NOSE score at 6-months follow-up compared to baseline was −48.8 (n = 1730, 95% CI: −54.6 to −42.9). Conclusions: Functional septoplasty with or without turbinate surgery shows a critical improvement of obstructive symptoms and quality of life according to the validated NOSE score. Level of Evidence: NA Laryngoscope, 133:3237–3246, 2023.