The subject of the present invention is a peptide, natural or synthetic, which comprises an amino acid sequence that has at least 80% sequence identity with the sequence SDRSLHLEANEKGENVNVHVTKTRADKSKIKVSVRQYADINEKGEAQYKCP-VAQLE (SEQ ID NO: 1). A further object of the present invention is said peptide which has at least 80% sequence identity with the sequence SEQ ID NO: 1 which is a JNK3 inhibitor for use in the prevention and / or treatment of neurodegenerative or neurodevel-opmental diseases.

JNK3 INHIBITORY PEPTIDES / T. Borsello, M. Falconi, D. Di Marino.

JNK3 INHIBITORY PEPTIDES

T. Borsello
Primo
;
2023

Abstract

The subject of the present invention is a peptide, natural or synthetic, which comprises an amino acid sequence that has at least 80% sequence identity with the sequence SDRSLHLEANEKGENVNVHVTKTRADKSKIKVSVRQYADINEKGEAQYKCP-VAQLE (SEQ ID NO: 1). A further object of the present invention is said peptide which has at least 80% sequence identity with the sequence SEQ ID NO: 1 which is a JNK3 inhibitor for use in the prevention and / or treatment of neurodegenerative or neurodevel-opmental diseases.
UNIV DEGLI STUDI MILANO; 75%
UNIV DEGLI STUDI DI ROMA TOR VERGATA;20%
UNIV POLITECNICA DELLE MARCHE 5%
US2023192785A1
US17/998,411
IT202000011176
22-giu-2023
Specific JNK3 inhibitor, in silico peptide design, stress-signalling pathway, synaptic dysfunction, neuroprotection, cell permeable peptide, brain diseases.
Settore BIOS-01/D - Biologia farmaceutica
Settore BIOS-11/A - Farmacologia
Settore BIOS-08/A - Biologia molecolare
https://worldwide.espacenet.com/patent/search?q=pn=US2023192785A1
JNK3 INHIBITORY PEPTIDES / T. Borsello, M. Falconi, D. Di Marino.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/1127795
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