Cattaneo et al. used genetic fate mapping in murine models to test the adipogenic potential of distinct cell types of the vascular wall. These parallel lineage-tracing experiments reveal that fibroblasts are the sole vascular cell type with significant adipocyte progenitor activity, giving rise to brown, beige, and white adipocytes.
Parallel Lineage-Tracing Studies Establish Fibroblasts as the Prevailing In Vivo Adipocyte Progenitor / P. Cattaneo, D. Mukherjee, S. Spinozzi, L. Zhang, V. Larcher, W.B. Stallcup, H. Kataoka, J. Chen, S. Dimmeler, S.M. Evans, N. Guimaraes-Camboa. - In: CELL REPORTS. - ISSN 2211-1247. - 30:2(2020), pp. 571-582. [10.1016/j.celrep.2019.12.046]
Parallel Lineage-Tracing Studies Establish Fibroblasts as the Prevailing In Vivo Adipocyte Progenitor
P. CattaneoPrimo
;
2020
Abstract
Cattaneo et al. used genetic fate mapping in murine models to test the adipogenic potential of distinct cell types of the vascular wall. These parallel lineage-tracing experiments reveal that fibroblasts are the sole vascular cell type with significant adipocyte progenitor activity, giving rise to brown, beige, and white adipocytes.
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