When biocatalysis meets flow chemistry

The number of biocatalyzed reactions in the industrial context is growing rapidly together with our understanding on how we can maximize the enzyme productivity increasing catalyst efficiency and stability. Although biocatalysis is nowadays identified as a greener way to operate in chemistry, its incorporation in flow reactors has lately come up as a powerful tool to enhance process productivity, sustainability and selectivity. This opinion article aims at describing the recent advances of this technology and future developments allowing for efficient, smart and environmentally-friendly strategies for process optimization and large scale production.