In this contribution, three deoxyestrone-based emissive lipofection agents are reported. Because of a centrally incorporated terephthalonitrile motif, these ligands can be classified as solution and solid-state emitters (SSSEs). With the attachment of tobramycin, these amphiphilic structures are able to form lipoplexes, mediating gene transfection of HeLa and HEK 293T cells.

Deoxyestrone-based lipofection agents with solution- and solid-state emission properties / A. Huber, J. Koch, K. Rudolph, A. Höing, F. Rizzo, S.K. Knauer, J. Voskuhl. - In: ORGANIC & BIOMOLECULAR CHEMISTRY. - ISSN 1477-0520. - 21:28(2023), pp. 5762-5767. [10.1039/D3OB00656E]

Deoxyestrone-based lipofection agents with solution- and solid-state emission properties

F. Rizzo;
2023

Abstract

In this contribution, three deoxyestrone-based emissive lipofection agents are reported. Because of a centrally incorporated terephthalonitrile motif, these ligands can be classified as solution and solid-state emitters (SSSEs). With the attachment of tobramycin, these amphiphilic structures are able to form lipoplexes, mediating gene transfection of HeLa and HEK 293T cells.
Settore CHEM-05/A - Chimica organica
Settore CHEM-06/A - Fondamenti chimici delle tecnologie
2023
Article (author)
File in questo prodotto:
File Dimensione Formato  
Huber et al. - 2023 - Deoxyestrone-based lipofection agents with solutio.pdf

accesso aperto

Descrizione: Communication
Tipologia: Publisher's version/PDF
Dimensione 1.47 MB
Formato Adobe PDF
1.47 MB Adobe PDF Visualizza/Apri
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/1106768
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 2
  • ???jsp.display-item.citation.isi??? 2
social impact