While precision medicine is still a challenge in rheumatic disease, in recent years many advances have been made regarding pathogenesis, the treatment of inflammatory arthropathies, and their interaction. New insight into the role of inflammasome and synovial tissue macrophage subsets as predictors of drug response give hope for future tailored therapeutic strategies and a personalized medicine approach in inflammatory arthropathies. Here, we discuss the main pathogenetic mechanisms and therapeutic approaches towards precision medicine in rheumatoid arthritis from the 2022 International GISEA/OEG Symposium.

From Bench to Bedside in Rheumatoid Arthritis from the “2022 GISEA International Symposium” / A. Vitale, S. Alivernini, R. Caporali, G. Cassone, D. Bruno, L. Cantarini, G. Lopalco, M. Rossini, F. Atzeni, E.G. Favalli, F. Conti, E. Gremese, F. Iannone, G.F. Ferraccioli, G. Lapadula, M. Sebastiani. - In: JOURNAL OF CLINICAL MEDICINE. - ISSN 2077-0383. - 12:2(2023), pp. 527.1-527.12. (Intervento presentato al convegno GISEA Symposium tenutosi a Trani nel 2022) [10.3390/jcm12020527].

From Bench to Bedside in Rheumatoid Arthritis from the “2022 GISEA International Symposium”

R. Caporali;E.G. Favalli;
2023

Abstract

While precision medicine is still a challenge in rheumatic disease, in recent years many advances have been made regarding pathogenesis, the treatment of inflammatory arthropathies, and their interaction. New insight into the role of inflammasome and synovial tissue macrophage subsets as predictors of drug response give hope for future tailored therapeutic strategies and a personalized medicine approach in inflammatory arthropathies. Here, we discuss the main pathogenetic mechanisms and therapeutic approaches towards precision medicine in rheumatoid arthritis from the 2022 International GISEA/OEG Symposium.
inflammasome; inflammatory arthropathies; pathogenesis; synovial tissue macrophage; therapy
Settore MED/16 - Reumatologia
2023
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/1068889
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