Purpose: To review the literature on the topic, to suggest a common line of treatment applicable across a wide community of specialists, and to contribute in maintaining the high level of interest in this disease. Methods: A comprehensive and exhaustive review of the literature was performed, identifying hundreds of articles on the topic. Results: Peyronie's disease is a condition that has been recognized, studied, and treated for centuries; despite this, if one excludes surgery in cases in which the deformity is stable, no clear treatment (or line of treatment) is available for complete relief of signs and symptoms. Treatment options were divided into local, oral, and injection therapy, and a wide variety of drugs, remedies, and options were identified. Conclusions: Low-intensity extracorporeal shock wave therapy, vacuum therapy, penile traction therapy, phosphodiesterase type 5 inhibitors, hyaluronic acid, and collagenase of Clostridium histolyticum may be recommended only in specific contexts. Further studies on individual options or potential combinations are required.

Conservative treatment of Peyronie’s disease: a guide / M. Cosentino, M. Di Nauta, L. Boeri, G. Ferraioli, G. Lucignani, A. Ricapito, F. Gadda, M. Iafrate, M. Mancini, F. Dal Moro, E. Ruiz-Castañe, C. Bettocchi, E. Montanari, N. Sofikitis. - In: WORLD JOURNAL OF UROLOGY. - ISSN 1433-8726. - 42:1(2024), pp. 317.1-317.9. [10.1007/s00345-024-04975-6]

Conservative treatment of Peyronie’s disease: a guide

G. Lucignani;E. Montanari
Penultimo
;
2024

Abstract

Purpose: To review the literature on the topic, to suggest a common line of treatment applicable across a wide community of specialists, and to contribute in maintaining the high level of interest in this disease. Methods: A comprehensive and exhaustive review of the literature was performed, identifying hundreds of articles on the topic. Results: Peyronie's disease is a condition that has been recognized, studied, and treated for centuries; despite this, if one excludes surgery in cases in which the deformity is stable, no clear treatment (or line of treatment) is available for complete relief of signs and symptoms. Treatment options were divided into local, oral, and injection therapy, and a wide variety of drugs, remedies, and options were identified. Conclusions: Low-intensity extracorporeal shock wave therapy, vacuum therapy, penile traction therapy, phosphodiesterase type 5 inhibitors, hyaluronic acid, and collagenase of Clostridium histolyticum may be recommended only in specific contexts. Further studies on individual options or potential combinations are required.
Acute phase; Conservative treatment; Curvature; Medical treatment; Peyronie’s disease
Settore MED/24 - Urologia
Settore FIS/02 - Fisica Teorica, Modelli e Metodi Matematici
2024
13-mag-2024
Article (author)
File in questo prodotto:
File Dimensione Formato  
s00345-024-04975-6.pdf

accesso riservato

Tipologia: Publisher's version/PDF
Dimensione 836.31 kB
Formato Adobe PDF
836.31 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/1052131
Citazioni
  • ???jsp.display-item.citation.pmc??? 0
  • Scopus 0
  • ???jsp.display-item.citation.isi??? ND
social impact