Visceral leishmaniasis is a life-threatening disease endemic in tropical and subtropical regions and in the Mediterranean basin. Two species (Leishmania infantum/chagasi and Leishmania donovani) with different host reservoirs are responsible for visceral disease. The infection is usually transmitted by phlebotomine sandflies, whereas vertical and blood transfusion transmission is rarely observed. We report a 35-year-old Italian pregnant woman in the 26th gestational week presenting with progressive fatigue, intermittent fever, and pancytopenia who finally was diagnosed with visceral leishmaniasis. She had treatment with liposomal amphotericin B and delivered at week 38 a baby small for gestational age. The newborn had a positive Leishmania serology that turned negative at 6 months of age.

Visceral Leishmaniasis During Pregnancy: A Case Report / S. Antinori, L. Milazzo, A. Behring, B. Caloni, L. Meroni. - In: ANNALS OF INTERNAL MEDICINE. CLINICAL CASES. - ISSN 2767-7664. - 3:4(2024 Apr 02), pp. e231380.1-e231380.3. [10.7326/aimcc.2023.1380]

Visceral Leishmaniasis During Pregnancy: A Case Report

S. Antinori
Primo
;
A. Behring;B. Caloni
Penultimo
;
2024

Abstract

Visceral leishmaniasis is a life-threatening disease endemic in tropical and subtropical regions and in the Mediterranean basin. Two species (Leishmania infantum/chagasi and Leishmania donovani) with different host reservoirs are responsible for visceral disease. The infection is usually transmitted by phlebotomine sandflies, whereas vertical and blood transfusion transmission is rarely observed. We report a 35-year-old Italian pregnant woman in the 26th gestational week presenting with progressive fatigue, intermittent fever, and pancytopenia who finally was diagnosed with visceral leishmaniasis. She had treatment with liposomal amphotericin B and delivered at week 38 a baby small for gestational age. The newborn had a positive Leishmania serology that turned negative at 6 months of age.
Amphotericin; Epstein–Barr virus; Labor and delivery; Leishmaniasis; Liposomal amphotericin B; Pregnancy; Tropical diseases; Vertical transmission; Visceral leishmaniasis;
Settore MED/42 - Igiene Generale e Applicata
2-apr-2024
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/1050469
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