Updating the approaches to define susceptibility and resistance to anti-tuberculosis agents: implications for diagnosis and treatment

Georghiou, S.B.; Rodwell, T.C.; Korobitsyn, A.; Abbadi, S.H.; Ajbani, K.; Alffenaar, J.-.; Alland, D.; Alvarez, N.; Andres, S.; Ardizzoni, E.; Aubry, A.; Baldan, R.; Ballif, M.; Barilar, I.; Bottger, E.C.; Chakravorty, S.; Claxton, P.M.; Cirillo, D.M.; Comas, I.; Coulter, C.; Denkinger, C.M.; Derendinger, B.; Desmond, E.P.; De Steenwinkel, J.E.M.; Dheda, K.; Diacon, A.H.; Dolinger, D.L.; Dooley, K.E.; Egger, M.; Ehsani, S.; Farhat, M.R.; Fattorini, L.; Finci, I.; Le Ray, L.F.; Furio, V.; Groenheit, R.; Gumbo, T.; Heysell, S.K.; Hillemann, D.; Hoffmann, H.; Hsueh, P.-.; Hu, Y.; Huang, H.; Hussain, A.; Ismail, F.; Izumi, K.; Jagielski, T.; Johnson, J.L.; Kambli, P.; Kaniga, K.; Eranga Karunaratne, G.H.R.; Sharma, M.K.; Keller, P.M.; Kelly, E.C.; Kholina, M.; Kohli, M.; Kranzer, K.; Laurenson, I.F.; Limberis, J.; Grace Lin, S.-.; Liu, Y.; Lopez-Gavin, A.; Lyander, A.; Machado, D.; Martinez, E.; Masood, F.; Mitarai, S.; Mvelase, N.R.; Niemann, S.; Nikolayevskyy, V.; Maurer, F.P.; Merker, M.; Miotto, P.; Omar, S.V.; Otto-Knapp, R.; Palaci, M.; Gutierrez, J.J.P.; Peacock, S.J.; Peloquin, C.A.; Perera, J.; Pierre-Audigier, C.; Pholwat, S.; Posey, J.E.; Prammananan, T.; Rigouts, L.; Robledo, J.; Rockwood, N.; Rodrigues, C.; Salfinger, M.; Schechter, M.C.; Seifert, M.; Sengstake, S.; Shinnick, T.; Shubladze, N.; Sintchenko, V.; Sirgel, F.; Somasundaram, S.; Sterling, T.R.; Spitaleri, A.; Streicher, E.; Supply, P.; Svensson, E.; Tagliani, E.; Tahseen, S.; Takaki, A.; Theron, G.; Torrea, G.; Van Deun, A.; Van Ingen, J.; Van Rie, A.; Van Soolingen, D.; Vargas, R.; Venter, A.; Veziris, N.; Villellas, C.; Viveiros, M.; Warren, R.; Wen, S.; Werngren, J.; Wilkinson, R.J.; Yang, C.; Ferda Yilmaz, F.; Zhang, T.; Zimenkov, D.; Ismail, N.; Schon, T.; Koser, C.U.

doi:10.1183/13993003.00166-2022

Inappropriately high breakpoints have resulted in systematic false-susceptible AST results to anti-TB drugs. MIC, PK/PD and clinical outcome data should be combined when setting breakpoints to minimise the emergence and spread of antimicrobial resistance. https://bit.ly/3i43wb6

Updating the approaches to define susceptibility and resistance to anti-tuberculosis agents: implications for diagnosis and treatment / S.B. Georghiou, T.C. Rodwell, A. Korobitsyn, S.H. Abbadi, K. Ajbani, J.-. Alffenaar, D. Alland, N. Alvarez, S. Andres, E. Ardizzoni, A. Aubry, R. Baldan, M. Ballif, I. Barilar, E.C. Bottger, S. Chakravorty, P.M. Claxton, D.M. Cirillo, I. Comas, C. Coulter, C.M. Denkinger, B. Derendinger, E.P. Desmond, J.E.M. de Steenwinkel, K. Dheda, A.H. Diacon, D.L. Dolinger, K.E. Dooley, M. Egger, S. Ehsani, M.R. Farhat, L. Fattorini, I. Finci, L.F. Le Ray, V. Furio, R. Groenheit, T. Gumbo, S.K. Heysell, D. Hillemann, H. Hoffmann, P.-. Hsueh, Y. Hu, H. Huang, A. Hussain, F. Ismail, K. Izumi, T. Jagielski, J.L. Johnson, P. Kambli, K. Kaniga, G.H.R. Eranga Karunaratne, M.K. Sharma, P.M. Keller, E.C. Kelly, M. Kholina, M. Kohli, K. Kranzer, I.F. Laurenson, J. Limberis, S.-. Grace Lin, Y. Liu, A. Lopez-Gavin, A. Lyander, D. Machado, E. Martinez, F. Masood, S. Mitarai, N.R. Mvelase, S. Niemann, V. Nikolayevskyy, F.P. Maurer, M. Merker, P. Miotto, S.V. Omar, R. Otto-Knapp, M. Palaci, J.J.P. Gutierrez, S.J. Peacock, C.A. Peloquin, J. Perera, C. Pierre-Audigier, S. Pholwat, J.E. Posey, T. Prammananan, L. Rigouts, J. Robledo, N. Rockwood, C. Rodrigues, M. Salfinger, M.C. Schechter, M. Seifert, S. Sengstake, T. Shinnick, N. Shubladze, V. Sintchenko, F. Sirgel, S. Somasundaram, T.R. Sterling, A. Spitaleri, E. Streicher, P. Supply, E. Svensson, E. Tagliani, S. Tahseen, A. Takaki, G. Theron, G. Torrea, A. Van Deun, J. van Ingen, A. Van Rie, D. van Soolingen, R. Vargas, A. Venter, N. Veziris, C. Villellas, M. Viveiros, R. Warren, S. Wen, J. Werngren, R.J. Wilkinson, C. Yang, F. Ferda Yilmaz, T. Zhang, D. Zimenkov, N. Ismail, T. Schon, C.U. Koser. - In: EUROPEAN RESPIRATORY JOURNAL. - ISSN 0903-1936. - 59:4(2022), pp. 2200166.1-2200166.11. [10.1183/13993003.00166-2022]

Updating the approaches to define susceptibility and resistance to anti-tuberculosis agents: implications for diagnosis and treatment

Georghiou S. B.;Rodwell T. C.;Korobitsyn A.;Abbadi S. H.;Ajbani K.;Alffenaar J. -W.;Alland D.;Alvarez N.;Andres S.;Ardizzoni E.;Aubry A.;Baldan R.;Ballif M.;Barilar I.;Bottger E. C.;Chakravorty S.;Claxton P. M.;Cirillo D. M.;Comas I.;Coulter C.;Denkinger C. M.;Derendinger B.;Desmond E. P.;de Steenwinkel J. E. M.;Dheda K.;Diacon A. H.;Dolinger D. L.;Dooley K. E.;Egger M.;Ehsani S.;Farhat M. R.;Fattorini L.;Finci I.;Le Ray L. F.;Furio V.;Groenheit R.;Gumbo T.;Heysell S. K.;Hillemann D.;Hoffmann H.;Hsueh P. -R.;Hu Y.;Huang H.;Hussain A.;Ismail F.;Izumi K.;Jagielski T.;Johnson J. L.;Kambli P.;Kaniga K.;Eranga Karunaratne G. H. R.;Sharma M. K.;Keller P. M.;Kelly E. C.;Kholina M.;Kohli M.;Kranzer K.;Laurenson I. F.;Limberis J.;Grace Lin S. -Y.;Liu Y.;Lopez-Gavin A.;Lyander A.;Machado D.;Martinez E.;Masood F.;Mitarai S.;Mvelase N. R.;Niemann S.;Nikolayevskyy V.;Maurer F. P.;Merker M.;Miotto P.;Omar S. V.;Otto-Knapp R.;Palaci M.;Gutierrez J. J. P.;Peacock S. J.;Peloquin C. A.;Perera J.;Pierre-Audigier C.;Pholwat S.;Posey J. E.;Prammananan T.;Rigouts L.;Robledo J.;Rockwood N.;Rodrigues C.;Salfinger M.;Schechter M. C.;Seifert M.;Sengstake S.;Shinnick T.;Shubladze N.;Sintchenko V.;Sirgel F.;Somasundaram S.;Sterling T. R.;A. Spitaleri;Streicher E.;Supply P.;Svensson E.;Tagliani E.;Tahseen S.;Takaki A.;Theron G.;Torrea G.;Van Deun A.;van Ingen J.;Van Rie A.;van Soolingen D.;Vargas R.;Venter A.;Veziris N.;Villellas C.;Viveiros M.;Warren R.;Wen S.;Werngren J.;Wilkinson R. J.;Yang C.;Ferda Yilmaz F.;Zhang T.;Zimenkov D.;Ismail N.;Schon T.;Koser C. U.

2022

Abstract

Inappropriately high breakpoints have resulted in systematic false-susceptible AST results to anti-TB drugs. MIC, PK/PD and clinical outcome data should be combined when setting breakpoints to minimise the emergence and spread of antimicrobial resistance. https://bit.ly/3i43wb6

Scheda breve

Scheda completa

Scheda completa (DC)

	Settori scientifico-disciplinari dell'articolo (sola visualizzazione)
	
				Settore BIO/10 - Biochimica
			
	Settori scientifico-disciplinari dell'articolo (validi dal 09/05/2024)
	
				Settore BIOS-07/A - Biochimica
			
	Data di pubblicazione
	
				2022
			
	Rivista in ANCE
	
				EUROPEAN RESPIRATORY JOURNAL
			
	DOI
	
				https://dx.doi.org/10.1183/13993003.00166-2022
			
	Tipologia
	
				Article (author)
			
	Appare nelle tipologie:
	
				01 - Articolo su periodico

File in questo prodotto:

File	Dimensione	Formato
Eur Respir J-2022--2200166.pdf accesso aperto Descrizione: article Tipologia: Publisher's version/PDF Dimensione 405.81 kB Formato Adobe PDF Visualizza/Apri	405.81 kB	Adobe PDF	Visualizza/Apri

Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/1047648

Citazioni

14

24

24

ND

IRIS Institutional Research Information System - AIR Archivio Istituzionale della Ricerca