Fetal brain development is a complex process involving different stages of growth and organization which are crucial for the development of brain circuits and neural connections. Fetal atlases and labeled datasets are promising tools to investigate prenatal brain development. They support the identification of atypical brain patterns, providing insights into potential early signs of clinical conditions. In a nutshell, prenatal brain imaging and post-processing via modern tools are a cutting-edge field that will significantly contribute to the advancement of our understanding of fetal development. In this work, we first provide terminological clarification for specific terms (i.e., “brain template” and “brain atlas”), highlighting potentially misleading interpretations related to inconsistent use of terms in the literature. We discuss the major structures and neurodevelopmental milestones characterizing fetal brain ontogenesis. Our main contribution is the systematic review of 18 prenatal brain atlases and 3 datasets. We also tangentially focus on clinical, research, and ethical implications of prenatal neuroimaging.

Fetal brain MRI atlases and datasets: A review / T. Ciceri, L. Casartelli, F. Montano, S. Conte, L. Squarcina, A. Bertoldo, N. Agarwal, P. Brambilla, D. Peruzzo. - In: NEUROIMAGE. - ISSN 1053-8119. - 292:(2024 Apr 15), pp. 120603.1-120603.14. [10.1016/j.neuroimage.2024.120603]

Fetal brain MRI atlases and datasets: A review

S. Conte;L. Squarcina;P. Brambilla
Penultimo
;
2024

Abstract

Fetal brain development is a complex process involving different stages of growth and organization which are crucial for the development of brain circuits and neural connections. Fetal atlases and labeled datasets are promising tools to investigate prenatal brain development. They support the identification of atypical brain patterns, providing insights into potential early signs of clinical conditions. In a nutshell, prenatal brain imaging and post-processing via modern tools are a cutting-edge field that will significantly contribute to the advancement of our understanding of fetal development. In this work, we first provide terminological clarification for specific terms (i.e., “brain template” and “brain atlas”), highlighting potentially misleading interpretations related to inconsistent use of terms in the literature. We discuss the major structures and neurodevelopmental milestones characterizing fetal brain ontogenesis. Our main contribution is the systematic review of 18 prenatal brain atlases and 3 datasets. We also tangentially focus on clinical, research, and ethical implications of prenatal neuroimaging.
Brain atlas; Brain dataset; Fetus; Magnetic resonance imaging;
Settore ING-INF/06 - Bioingegneria Elettronica e Informatica
   Assegnazione Dipartimenti di Eccellenza 2023-2027 - Dipartimento di FISIOPATOLOGIA MEDICO-CHIRURGICA E DEI TRAPIANTI
   DECC23_009
   MINISTERO DELL'UNIVERSITA' E DELLA RICERCA
15-apr-2024
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/1047191
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