Wildlife diseases are contributing to the current Earth’s sixth mass extinction; one disease, chytridiomycosis, has caused mass amphibian die-offs. While global spread of a hypervirulent lineage of the fungus Batrachochytrium dendrobatidis (BdGPL) causes unprecedented loss of vertebrate diversity by decimating amphibian populations, its impact on amphibian communities is highly variable across regions. Here, we combine field data with in vitro and in vivo trials that demonstrate the presence of a markedly diverse variety of low virulence isolates of BdGPL in northern European amphibian communities. Pre-exposure to some of these low virulence isolates protects against disease following subsequent exposure to highly virulent BdGPL in midwife toads (Alytes obstetricans) and alters infection dynamics of its sister species B. salamandrivorans in newts (Triturus marmoratus), but not in salamanders (Salamandra salamandra). The key role of pathogen virulence in the complex host-pathogen-environment interaction supports efforts to limit pathogen pollution in a globalized world.

Presence of low virulence chytrid fungi could protect European amphibians from more deadly strains / M.S. Greener, E. Verbrugghe, M. Kelly, M. Blooi, W. Beukema, S. Canessa, S. Carranza, S. Croubels, N. De Troyer, D. Fernandez-Giberteau, P. Goethals, L. Lens, Z. Li, G. Stegen, D. Strubbe, R. van Leeuwenberg, S. Van Praet, M. Vila-Escale, M. Vervaeke, F. Pasmans, A. Martel. - In: NATURE COMMUNICATIONS. - ISSN 2041-1723. - 11:1(2020 Oct 26), pp. 5393.1-5393.11. [10.1038/s41467-020-19241-7]

Presence of low virulence chytrid fungi could protect European amphibians from more deadly strains

S. Canessa;
2020

Abstract

Wildlife diseases are contributing to the current Earth’s sixth mass extinction; one disease, chytridiomycosis, has caused mass amphibian die-offs. While global spread of a hypervirulent lineage of the fungus Batrachochytrium dendrobatidis (BdGPL) causes unprecedented loss of vertebrate diversity by decimating amphibian populations, its impact on amphibian communities is highly variable across regions. Here, we combine field data with in vitro and in vivo trials that demonstrate the presence of a markedly diverse variety of low virulence isolates of BdGPL in northern European amphibian communities. Pre-exposure to some of these low virulence isolates protects against disease following subsequent exposure to highly virulent BdGPL in midwife toads (Alytes obstetricans) and alters infection dynamics of its sister species B. salamandrivorans in newts (Triturus marmoratus), but not in salamanders (Salamandra salamandra). The key role of pathogen virulence in the complex host-pathogen-environment interaction supports efforts to limit pathogen pollution in a globalized world.
Settore BIO/05 - Zoologia
26-ott-2020
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/1040207
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