In Particle Therapy, safety margins are applied around the tumor to account for the beam range uncertainties and ensure an adequate dose coverage of the tumor volume during the therapy. The reduction of safety margins is in great demand in order to diminish the Particle Therapy side effects especially in the case of treatment of tumors close to Organs at Risk (OAR) and of pediatric patients. To this aim, beam range monitoring techniques are being developed by the scientific community, most of all based on the detection of secondary particles produced by the nuclear interactions of the beam with the patient’s tissue nuclei. In this contribution, a novel beam range monitoring technique is proposed, based on the detection of prompt photons exploiting the pair production mechanism. The proof of principle of the PAir PRoduction Imaging ChAmber (PAPRICA) is studied through the development of a Monte Carlo simulation and the detector performances toward a more realistic scenario are determined.

PAPRICA: The Pair Production Imaging Chamber—Proof of Principle / M. Toppi, I. Avanzolini, L. Balconi, G. Battistoni, G. Calvi, M. De Simoni, Y. Dong, A. Fantoni, G. Franciosini, M. Marafini, M. Fischetti, V. Muccifora, S. Muraro, V. Patera, F. Ronchetti, A. Sarti, A. Sciubba, G. Traini, S.M. Valle, I. Mattei. - In: FRONTIERS IN PHYSICS. - ISSN 2296-424X. - 9:(2021), pp. 568139.1-568139.13. [10.3389/fphy.2021.568139]

PAPRICA: The Pair Production Imaging Chamber—Proof of Principle

L. Balconi;
2021

Abstract

In Particle Therapy, safety margins are applied around the tumor to account for the beam range uncertainties and ensure an adequate dose coverage of the tumor volume during the therapy. The reduction of safety margins is in great demand in order to diminish the Particle Therapy side effects especially in the case of treatment of tumors close to Organs at Risk (OAR) and of pediatric patients. To this aim, beam range monitoring techniques are being developed by the scientific community, most of all based on the detection of secondary particles produced by the nuclear interactions of the beam with the patient’s tissue nuclei. In this contribution, a novel beam range monitoring technique is proposed, based on the detection of prompt photons exploiting the pair production mechanism. The proof of principle of the PAir PRoduction Imaging ChAmber (PAPRICA) is studied through the development of a Monte Carlo simulation and the detector performances toward a more realistic scenario are determined.
pair production; particle therapy; prompt photons; range monitoring; reconstruction
Settore FIS/07 - Fisica Applicata(Beni Culturali, Ambientali, Biol.e Medicin)
2021
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/1030372
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