For many years the extracellular matrix (ECM) was thought to serve only as a structural support for tissues. However, as early as 1966, Hauschka and Konigsberg [1] showed that interstitial collagen promoted the conversion of myoblasts to myotubes, and shortly thereafter it was shown that both collagen [2] and glycosaminoglycans [3] play a crucial role in salivary gland morphogenesis.
Role of extracellular matrix remodeling in Advanced Biocompatibility / M. Cannas, M. Bosetti, M. Sabbatini, F. Reno' - In: Tissue Engineering and Novel Delivery System / [a cura di] M.J. Yaszemski, D.J. Trantolo, K.-U. Lewandrowski, V. Hasirci, D.E. Altobelli, D.L. Wise. - [s.l] : CRC Press, 2003. - ISBN 9780429223785. - pp. 1-30
Role of extracellular matrix remodeling in Advanced Biocompatibility
F. Reno'
2003
Abstract
For many years the extracellular matrix (ECM) was thought to serve only as a structural support for tissues. However, as early as 1966, Hauschka and Konigsberg [1] showed that interstitial collagen promoted the conversion of myoblasts to myotubes, and shortly thereafter it was shown that both collagen [2] and glycosaminoglycans [3] play a crucial role in salivary gland morphogenesis.
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