Biological valve failure (BVF) is an inevitable condition that compromises the durability of biological heart valves (BHVs). It stems from various causes, including rejection, thrombosis, and endocarditis, leading to a critical state of valve dysfunction. Echocardiography, cardiac computed tomography, cardiac magnetic resonance, and nuclear imaging play pivotal roles in the diagnostic multimodality workup of BVF. By providing a comprehensive overview of the pathophysiology of BVF and the diagnostic approaches in different clinical scenarios, this review aims to aid clinicians in their decision-making process. The significance of early detection and appropriate management of BVF cannot be overstated, as these directly impact patients' prognosis and their overall quality of life. Ensuring timely intervention and tailored treatments will not only improve outcomes but also alleviate the burden of this condition on patients' life. By prioritizing comprehensive assessments and adopting the latest advancements in diagnostic technology, medical professionals can significantly enhance their ability to manage BVF effectively.

Early Biological Valve Failure: Structural Valve Degeneration, Thrombosis, or Endocarditis? / F. Fazzari, A. Baggiano, L. Fusini, S. Ghulam Ali, P. Gripari, D. Junod, M.E. Mancini, R. Maragna, S. Mushtaq, G. Pontone, M. Pepi, M. Muratori. - In: JOURNAL OF CLINICAL MEDICINE. - ISSN 2077-0383. - 12:17(2023 Sep 03), pp. 5740.1-5740.23. [10.3390/jcm12175740]

Early Biological Valve Failure: Structural Valve Degeneration, Thrombosis, or Endocarditis?

A. Baggiano
Secondo
;
D. Junod;G. Pontone;
2023

Abstract

Biological valve failure (BVF) is an inevitable condition that compromises the durability of biological heart valves (BHVs). It stems from various causes, including rejection, thrombosis, and endocarditis, leading to a critical state of valve dysfunction. Echocardiography, cardiac computed tomography, cardiac magnetic resonance, and nuclear imaging play pivotal roles in the diagnostic multimodality workup of BVF. By providing a comprehensive overview of the pathophysiology of BVF and the diagnostic approaches in different clinical scenarios, this review aims to aid clinicians in their decision-making process. The significance of early detection and appropriate management of BVF cannot be overstated, as these directly impact patients' prognosis and their overall quality of life. Ensuring timely intervention and tailored treatments will not only improve outcomes but also alleviate the burden of this condition on patients' life. By prioritizing comprehensive assessments and adopting the latest advancements in diagnostic technology, medical professionals can significantly enhance their ability to manage BVF effectively.
biological heart valves; biological valve failure; bioprosthesis; endocarditis; multimodality imaging; rejection; structural valve degeneration; thrombosis
Settore MED/11 - Malattie dell'Apparato Cardiovascolare
3-set-2023
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/1006659
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