Introduction: We assessed the prevalence and clinical outcomes of segmental colitis associated with diverticulosis (SCAD) in patients with newly diagnosed diverticulosis. Methods: A 3-year international, multicenter, prospective cohort study was conducted involving 2,215 patients. Results: SCAD diagnosis was posed in 44 patients (30 male patients; median age: 64.5 years; prevalence of 1.99%, 95% confidence interval, 1.45%-2.66%). Patients with SCAD types D and B showed worse symptoms, higher fecal calprotectin values, needed more steroids, and reached less likely complete remission. Discussion: Although SCAD generally had a benign outcome, types B and D were associated with more severe symptoms and worse clinical course.
Prevalence and Natural History of Segmental Colitis Associated with Diverticulosis / A. Tursi, D. Piovani, G. Brandimarte, F. Di Mario, W. Elisei, M. Picchio, L. Allegretta, M.L. Annunziata, M. Bafutto, G. Bassotti, M.A. Bianco, R. Colucci, R. Conigliaro, D.L. Dumitrascu, R. Escalante, L. Ferrini, G. Forti, M. Franceschi, M.G. Graziani, F. Lammert, G. Latella, G. Maconi, D. Compare, G. Nardone, L. Camara De Castro Oliveira, E. Chaves Oliveira, S. Papagrigoriadis, A. Pietrzak, S. Pontone, I. Stundiene, G. Pranzo, M.C. Reichert, S. Rodinò, J. Regula, G. Scaccianoce, F. Scaldaferri, R. Vassallo, C. Zampaletta, A. Zullo, E. Spaziani, S. Bonovas, A. Papa, S. Danese. - In: THE AMERICAN JOURNAL OF GASTROENTEROLOGY. - ISSN 0002-9270. - (2023), pp. 1-5. [Epub ahead of print] [10.14309/ajg.0000000000002362]
Prevalence and Natural History of Segmental Colitis Associated with Diverticulosis
G. Maconi;
2023
Abstract
Introduction: We assessed the prevalence and clinical outcomes of segmental colitis associated with diverticulosis (SCAD) in patients with newly diagnosed diverticulosis. Methods: A 3-year international, multicenter, prospective cohort study was conducted involving 2,215 patients. Results: SCAD diagnosis was posed in 44 patients (30 male patients; median age: 64.5 years; prevalence of 1.99%, 95% confidence interval, 1.45%-2.66%). Patients with SCAD types D and B showed worse symptoms, higher fecal calprotectin values, needed more steroids, and reached less likely complete remission. Discussion: Although SCAD generally had a benign outcome, types B and D were associated with more severe symptoms and worse clinical course.
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