PAPLEKAJ, ARTEDA
PAPLEKAJ, ARTEDA
Dipartimento di Biotecnologie Mediche e Medicina Traslazionale
Potentiating LSD1 as an emerging therapeutic approach to preserve adaptive fear memory updating
2026 A. Paplekaj, A. Antoniazzi, E. Toffolo, E. Battaglioli, F. Rusconi
LSD1 splicing is regulated by the long non-coding RNA MALAT1 and orchestrates stress resilience in mammals
2026 A. Paplekaj, E. Romito, C. Forastieri, E. Toffolo, S. Briguglio, P. Pelucchi, E. Mosca, A. Chiodi, M. Viatore, M.P. Bonasoni, A.L. Santunione, F. Pirani, E. Maggioni, P. Brambilla, E. Battaglioli, F. Rusconi
MALAT1–nSR100–LSD1: a conserved regulatory axis controlling stress adaptation
2026 A. Paplekaj, E. Romito, C. Forastieri, E. Toffolo, P. Pelucchi, E. Mosca, A. Chiodi, M.P. Bonasoni, A.L. Santunione, F. Pirani, E. Battaglioli, F. Rusconi
Epigenetic Control of Anxiety through LSD1 Splice Switching
2026 A. Paplekaj, A. Antoniazzi, M. Italia, F. Gardoni, E. Battaglioli, F. Rusconi
Potentiating LSD1 via ASO-mediated exon skipping: an epigenetic approach to study fear memory
2026 A. Paplekaj, E. Codini, E. Toffolo, E. Battaglioli, F. Rusconi
Epigenetics in PTSD: potentiating LSD1 to Rewire Fear Memory Circuits
2025 A. Paplekaj, C. Forastieri, A. Antoniazzi, E. Codini., E. Toffolo, E. Battaglioli, F. Rusconi
Evidence-based approach to treat hyperexcitability in Rett syndrome through splicing modulation
2025 A. Paplekaj, C. Forastieri, A. Antoniazzi, C. Codini, E. Toffolo, F. Rusconi, E. Battaglioli
LSD1 Scale-Up: transitioning from cells to a pre-clinical RNA-based therapy approach for post-traumatic disorders
2024 A. Paplekaj, E. Romito, S. Testa, E. Toffolo, E. Battaglioli, F. Rusconi
Dissecting the Hippocampal Regulation of Approach-Avoidance Conflict: Integrative Perspectives From Optogenetics, Stress Response, and Epigenetics
2024 C. Forastieri, E. Romito, A. Paplekaj, E. Battaglioli, F. Rusconi
Extending MALAT1 activity to the modulation of LSD1 alternative splicing: a novel cell-autonomous mechanism devoted to neuronal homeostasis
2024 E. Romito, C. Forastieri, A. Paplekaj, A. De Donato, S. Testa, E. Toffolo, E. Battaglioli, F. Rusconi.
A novel role for LSD1 splicing modulation in homeostatic adaptation to chronic stress
2024 A. Paplekaj, C. Forastieri, E. Romito, A. de Donato, S. Testa, E. Toffolo, E. Battaglioli, F. Rusconi
A comprehensive protocol for efficient differentiation of human NPCs into electrically competent neurons
2024 E. Romito, I. Battistella, V. Plakhova, A. Paplekaj, C. Forastieri, E. Toffolo, C. Musio, L. Conti, E. Battaglioli, F. Rusconi
LSD1 and the lncRNA MALAT1: a mammalian epigenetic pathway involved in environmental adaptation
2023 E. Romito, C. Forastieri, A. De Donato, A. Paplekaj, E. Toffolo, E. Battaglioli, F. Rusconi