CASIRAGHI, VALERIA
CASIRAGHI, VALERIA
Dipartimento di Biotecnologie Mediche e Medicina Traslazionale
Induced Pluripotent Stem Cell (iPSC)-derived Microglia for ALS modeling
2025 E. Pellegrini, C. Lattuada, S. Invernizzi, V. Casiraghi, S. Santangelo, V. Silani, A. Ratti, P. Bossolasco
Characterization of human healthy i3 lower motor neurons exposed to CSF from ALS patients stratified by UNC13A and C9ORF72 genotype
2025 V. Casiraghi, E. Pellegrini, A. Brusati, S. Peverelli, S. Invernizzi, S. Santangelo, C. Colombrita, F. Verde, N. Ticozzi, V. Silani, A. Ratti
Unraveling the role of primary cilia in the pathogenesis of amyotrophic lateral sclerosis
2025 S. Invernizzi, V. Casarotto, V. Casiraghi, S. Santangelo, E. Pellegrini, P. Bossolasco, A. Ratti
Induced Pluripotent Stem Cell (iPSC)-derived Microglia and Organoids for neuronal disease modeling
2025 E. Pellegrini, C. Lattuada, S. Invernizzi, V. Casiraghi, S. Santangelo, V. Silani, A. Ratti, P. Bossolasco
Unraveling the role of NEK1 on primary cilia using mutant iPSC models
2025 S. Invernizzi, V. Casiraghi, V. Casarotto, S. Santangelo, E. Pellegrini, J. Landers, V. Silani, P. Bossolasco, A. Ratti
Characterization of human healthy i3 lower motor neurons exposed to CSF from ALS patients stratified by UNC13A and C9ORF72 genotype
2025 V. Casiraghi, E. Pellegrini, A. Brusati, S. Peverelli, S. Invernizzi, S. Santangelo, C. Colombrita, F. Verde, N. Ticozzi, V. Silani, A. Ratti
Modeling of TDP-43 proteinopathy by chronic oxidative stress identifies rapamycin as beneficial in ALS patient-derived 2D and 3D iPSC models
2025 V. Casiraghi, M.N. Sorce, S. Santangelo, S. Invernizzi, P. Bossolasco, C. Lattuada, C. Battaglia, M. Venturin, V. Silani, C. Colombrita, A. Ratti
Characterization of human i3 motor neurons exposed to CSF from ALS patients stratified by C9ORF72 and UNC13A genotype
2024 V. Casiraghi, E. Pellegrini, A. Brusati, S. Peverelli, S. Invernizzi, S. Santangelo, C. Colombrita, V. Silani, A. Ratti
Characterization of human i3 motor neurons exposed to CSF from ALS patients stratified by C9ORF72 and UNC13A genotype
2024 V. Casiraghi, E. Pellegrini, A. Brusati, S. Peverelli, S. Invernizzi, S. Santangelo, C. Colombrita, V. Silani, A. Ratti
Defective primary cilia in NEK1 and C9ORF72 iPSC-derived motoneurons and brain organoids
2024 S. Invernizzi, S. Santangelo, V. Casiraghi, S. Peverelli, P. Paola, Q. Angelo, V. Silani, P. Bossolasco, A. Ratti
AGGREGATION MECHANISMS OF TDP-43 PROTEIN IN RESPONSE TO STRESS IN AMYOTROPHIC LATERAL SCLEROSIS AND THERAPEUTIC APPROACHES
2024 V. Casiraghi
NEK1 haploinsufficiency worsens DNA damage, but not defective ciliogenesis, in C9ORF72 patient-derived iPSC-motoneurons
2024 S. Santangelo, S. Invernizzi, M.N. Sorce, V. Casiraghi, S. Peverelli, A. Brusati, C. Colombrita, N. Ticozzi, V. Silani, P. Bossolasco, A. Ratti
Quantification of serum TDP-43 and neurofilament light chain in patients with amyotrophic lateral sclerosis stratified by UNC13A genotype
2024 V. Casiraghi, I. Milone, A. Brusati, S. Peverelli, A. Doretti, B. Poletti, L. Maderna, C. Morelli, N. Ticozzi, V. Silani, F. Verde, A. Ratti
Modeling a novel N-terminal mutation of KIF5A gene in patient-derived iPSC-motoneurons
2024 S. Invernizzi, S. Santangelo, V. Casiraghi, P. Bossolasco, C. Fallini, S. Magri, A. Poletti, V. Silani, F. Taroni, A. Ratti
Induced Pluripotent Stem Cell (iPSC)-derived Microglia for ALS modeling
2024 E. Pellegrini, C. Lattuada, S. Invernizzi, V. Casiraghi, S. Santangelo, V. Silani, A. Ratti, P. Bossolasco
Induced Pluripotent Stem Cell (iPSC)-derived Microglia for ALS modeling
2024 E. Pellegrini, C. Lattuada, S. Invernizzi, V. Casiraghi, S. Santangelo, V. Silani, A. Ratti, P. Bossolasco
Characterization of human i3 motor neurons exposed to CSF from ALS patients stratified by C9ORF72 and UNC13A genotype
2024 V. Casiraghi, E. Pellegrini, A. Brusati, S. Peverelli, S. Invernizzi, S. Santangelo, C. Colombrita, V. Silani, A. Ratti
Defective primary cilia in NEK1 and C9ORF72 iPSC-derived motoneurons and brain organoids
2024 S. Invernizzi, S. Santangelo, V. Casiraghi, S. Peverelli, P. Paola, Q. Angelo, V. Silani, P. Bossolasco, A. Ratti
Rapamycin reverts TDP-43 splicing defects and mislocalization in human in vitro models of TDP-43 proteinopathy
2023 V. Casiraghi, C. Colombrita, S. Santangelo, S. Invernizzi, M.N. Sorce, P. Bossolasco, V. Silani, A. Ratti
U1 snRNA as a novel RNA-based therapeutic approach to modulate C9ORF72 pathology in patient-derived iPSC-motoneurons
2023 S. Invernizzi, S. Santangelo, E. Bussani, G. Romano, C. Colombrita, V. Casiraghi, M. Nice Sorce, P. Bossolasco, V. Silani, F. Pagani, A. Ratti