LANDSBERGER, NICOLETTA
LANDSBERGER, NICOLETTA
Dipartimento di Biotecnologie Mediche e Medicina Traslazionale
Advanced genetic therapies for the treatment of Rett syndrome: state of the art and future perspectives
2023 M. Palmieri, D. Pozzer, N. Landsberger
A comprehensive longitudinal study of magnetic resonance imaging identifies novel features of the Mecp2 deficient mouse brain
2023 S. Carli, L. Chaabane, G. De Rocco, E. Albizzati, I. Sormonta, S. Calligaro, P. Bonizzi, A. Frasca, N. Landsberger
Complex CDKL5 translational regulation and its potential role in CDKL5 deficiency disorder
2023 V. Ruggiero, C. Fagioli, S. de Pretis, V. Di Carlo, N. Landsberger, D. Zacchetti
Not Just Loss-of-Function Variations: Identification of a Hypermorphic Variant in a Patient With a CDKL5 Missense Substitution
2022 A. Frasca, E. Pavlidou, M. Bizzotto, Y. Gao, D. Balestra, M. Pinotti, H.A. Dahl, N.D. Mazarakis, N. Landsberger, M. Kinali
Identification of Region-Specific Cytoskeletal and Molecular Alterations in Astrocytes of Mecp2 Deficient Animals
2022 E. Albizzati, E. Florio, F. Miramondi, I. Sormonta, N. Landsberger, A. Frasca
In vivo magnetic resonance spectroscopy in the brain of Cdkl5 null mice reveals a metabolic profile indicative of mitochondrial dysfunctions
2021 S. Carli, L. Chaabane, C. Butti, C. De Palma, P. Aimar, C. Salio, A. Vignoli, M. Giustetto, N. Landsberger, A. Frasca
The enhancement of activity rescues the establishment of Mecp2 null neuronal phenotypes
2021 L. Scaramuzza, G. De Rocco, G. Desiato, C. Cobolli Gigli, M. Chiacchiaretta, F. Mirabella, D. Pozzi, M. De Simone, P. Conforti, M. Pagani, F. Benfenati, F. Cesca, F. Bedogni, N. Landsberger
MECP2 mutations affect ciliogenesis: a novel perspective for Rett syndrome and related disorders
2020 A. Frasca, E. Spiombi, M. Palmieri, E. Albizzati, M. Valente, A.L.B. Bergo, C. Kilstrup-Nielsen, F. Bianchi, V. Di Carlo, F. Di Cunto, N. Landsberger
Fingolimod modulates dendritic architecture in a BDNF-dependent manner
2020 A. Patnaik, E. Spiombi, A. Frasca, N. Landsberger, M. Zagrebelsky, M. Korte
The DNA repair protein ATM as target in autism spectrum disorder
2020 L. Pizzamiglio, E. Focchi, C. Cambria, L. Ponzoni, S. Ferrara, F. Bifari, G. Desiato, N. Landsberger, L. Murru, M. Passafaro, M. Sala, M. Matteoli, E. Menna, F. Antonucci
Aminoglycoside drugs induce efficient read-through of CDKL5 nonsense mutations, slightly restoring its kinase activity
2019 M. Fazzari, A. Frasca, F. Bifari, N. Landsberger
Splicing mutations impairing CDKL5 expression and activity can be efficiently rescued by U1snRNA-based therapy
2019 D. Balestra, D. Giorgio, M. Bizzotto, M. Fazzari, B.B. Zeev, M. Pinotti, N. Landsberger, A. Frasca
Progress in the development of in vivo redox measurements: New tools for longitudinal studies in Rett syndrome
2019 A. Frasca, F. Bedogni, N. Landsberger
Rescue of prepulse inhibition deficit and brain mitochondrial dysfunction by pharmacological stimulation of the central serotonin receptor 7 in a mouse model of CDKL5 Deficiency Disorder
2019 D. Vigli, L. Rusconi, D. Valenti, P. La Montanara, L. Cosentino, E. Lacivita, M. Leopoldo, E. Amendola, C. Gross, N. Landsberger, G. Laviola, C. Kilstrup-Nielsen, R.A. Vacca, B. De Filippis
Towards a consensus on developmental regression
2019 D. Zhang, F. Bedogni, S. Boterberg, C. Camfield, P. Camfield, T. Charman, L. Curfs, C. Einspieler, G. Esposito, B. De Filippis, R.P. Goin-Kochel, G.U. Hoglinger, D. Holzinger, A.-. Iosif, G.E. Lancioni, N. Landsberger, G. Laviola, E.M. Marco, M. Muller, J.L. Neul, K. Nielsen-Saines, A. Nordahl-Hansen, M.F. O'Reilly, S. Ozonoff, L. Poustka, H. Roeyers, M. Rankovic, J. Sigafoos, K. Tammimies, G.S. Townend, L. Zwaigenbaum, M. Zweckstetter, S. Bolte, P.B. Marschik
Cannabidivarin completely rescues cognitive deficits and delays neurological and motor defects in male Mecp2 mutant mice
2019 E. Zamberletti, M. Gabaglio, F. Piscitelli, J.S. Brodie, M. Woolley-Roberts, I. Barbiero, M. Tramarin, G. Binelli, N. Landsberger, C. Kilstrup-Nielsen, T. Rubino, V. Di Marzo, D. Parolaro
A Novel Mecp2Y120D Knock-in Model Displays Similar Behavioral Traits But Distinct Molecular Features Compared to the Mecp2-Null Mouse Implying Precision Medicine for the Treatment of Rett Syndrome
2019 A. Gandaglia, E. Brivio, S. Carli, M. Palmieri, F. Bedogni, G. Stefanelli, A. Bergo, B. Leva, C. Cattaneo, L. Pizzamiglio, M. Cicerone, V. Bianchi, C. Kilstrup-Nielsen, I. D'Annessa, D. Di Marino, P. D'Adamo, F. Antonucci, A. Frasca, N. Landsberger
Lack of Methyl-CpG Binding Protein 2 (MeCP2) Affects Cell Fate Refinement During Embryonic Cortical Development
2018 C.G. Clementina, S. Linda, D.S. Marco, R. Riccardo L, P. Davide, M. Pagani, N. Landsberger, F. Bedogni
Tyr120Asp mutation alters domain flexibility and dynamics of MeCP2 DNA binding domain leading to impaired DNA interaction : Atomistic characterization of a Rett syndrome causing mutation
2018 I. D'Annessa, A. Gandaglia, E. Brivio, G. Stefanelli, A. Frasca, N. Landsberger, D. Di Marino
The neurosteroid pregnenolone reverts microtubule derangement induced by the loss of a functional CDKL5-IQGAP1 complex
2017 I. Barbiero, D. Peroni, M. Tramarin, C. Chandola, L. Rusconi, N. Landsberger, C. Kilstrup-Nielsen