Introduction. Endocarditis is a rare complication of bacteraemia due to Listeria monocytogenes and is characterized by a high fatality rate (37–50 %). Recurrent infection by Listeria monocytogenes occurs even more rarely. Case presentation. We report a case of recurrent Listeria monocytogenes infection that resulted in severe endocarditis in a 66-year-old patient with an aortic valve prosthesis. Relapse was confirmed by pulsed-field gel electrophoresis (PFGE) and multi-locus sequence typing (MLST). Conclusion. Our case highlights that the molecular subtyping approach is an important tool for the detection of microbial reinfections and for the support of clinical diagnosis.

Molecular evidence of Listeria monocytogenes infection relapse in a severe case of endocarditis / G. Ciceri, M. Gori, S. Bianchi, G. Corrado, P. Panisi, A. Papa, E. Tanzi, M..M. Pontello. - In: JMM CASE REPORTS. - ISSN 2053-3721. - 4:9(2017 Sep 25), pp. e005115.1-e005115.4. [10.1099/jmmcr.0.005115]

Molecular evidence of Listeria monocytogenes infection relapse in a severe case of endocarditis

G. Ciceri
Co-primo
;
M. Gori
Co-primo
;
S. Bianchi;E. Tanzi
Penultimo
;
M..M. Pontello
Ultimo
2017

Abstract

Introduction. Endocarditis is a rare complication of bacteraemia due to Listeria monocytogenes and is characterized by a high fatality rate (37–50 %). Recurrent infection by Listeria monocytogenes occurs even more rarely. Case presentation. We report a case of recurrent Listeria monocytogenes infection that resulted in severe endocarditis in a 66-year-old patient with an aortic valve prosthesis. Relapse was confirmed by pulsed-field gel electrophoresis (PFGE) and multi-locus sequence typing (MLST). Conclusion. Our case highlights that the molecular subtyping approach is an important tool for the detection of microbial reinfections and for the support of clinical diagnosis.
Listeria monocytogenes; endocarditis; relapse; invasive listeriosis; surveillance; molecular subtyping
Settore MED/42 - Igiene Generale e Applicata
Settore MED/07 - Microbiologia e Microbiologia Clinica
25-set-2017
Article (author)
File in questo prodotto:
File Dimensione Formato  
jmmcr005115.pdf

accesso aperto

Tipologia: Publisher's version/PDF
Dimensione 179.77 kB
Formato Adobe PDF
179.77 kB Adobe PDF Visualizza/Apri
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/525554
Citazioni
  • ???jsp.display-item.citation.pmc??? 2
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact