Hetero-nanoparticles self-assembled from a conjugate bearing folic acid as the targeting agent, and another bearing paclitaxel as the active agent are reported. Hetero-nanoparticles containing varying percentages of folic acid conjugates are characterised, and their biological activity is determined.
Folic acid functionalization for targeting self-assembled paclitaxel-based nanoparticles / E. Colombo, D. Andrea Coppini, S. Maculan, P. Seneci, B. Santini, F. Testa, L. Salvioni, G. Maria Vanacore, M. Colombo, D. Passarella. - In: RSC ADVANCES. - ISSN 2046-2069. - 12:54(2022 Dec 12), pp. 35484-35493. [10.1039/D2RA06306A]
Folic acid functionalization for targeting self-assembled paclitaxel-based nanoparticles
E. ColomboPrimo
;P. Seneci;B. Santini;D. Passarella
Ultimo
2022
Abstract
Hetero-nanoparticles self-assembled from a conjugate bearing folic acid as the targeting agent, and another bearing paclitaxel as the active agent are reported. Hetero-nanoparticles containing varying percentages of folic acid conjugates are characterised, and their biological activity is determined.
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