Infant biscuits (IBs) are commonly used during the complementary feeding of infants from the 6th month of life. They contain wheat flour and dairy ingredients, which can release the opioid-acting peptides beta-casomorphins (BCMs) and gluten exorphins (GEs) after gastrointestinal digestion. In the present study, five model IBs were prepared with or without gluten and different powdered milk derivatives in the formulations. IBs were digested simulating an in vitro static gastrointestinal digestion for infants aged 6-12 months. BCMs and GEs were identified and quantified by UPLC/HR-MS. The amounts of BCM7 and the GE A5 were related to the beta-CN and gluten content of the formulations. To date, levels of BCMs and GEs in digests of IBs have not been reported in literature. This work represents an in vitro investigation regarding the release of opioid-acting peptides in IBs. It could add additional knowledge on complementary foods for infant health.
Model infant biscuits release the opioid-acting peptides milk β-casomorphins and gluten exorphins after in vitro gastrointestinal digestion / V. Pica, M. Stuknyte, F. Masotti, I. De Noni, S. Cattaneo. - In: FOOD CHEMISTRY. - ISSN 0308-8146. - 362:(2021 Nov 15), pp. 130262.1-130262.6. [10.1016/j.foodchem.2021.130262]
Model infant biscuits release the opioid-acting peptides milk β-casomorphins and gluten exorphins after in vitro gastrointestinal digestion
V. PicaPrimo
;M. StuknyteSecondo
;F. Masotti;I. De Noni
Penultimo
;S. CattaneoUltimo
2021
Abstract
Infant biscuits (IBs) are commonly used during the complementary feeding of infants from the 6th month of life. They contain wheat flour and dairy ingredients, which can release the opioid-acting peptides beta-casomorphins (BCMs) and gluten exorphins (GEs) after gastrointestinal digestion. In the present study, five model IBs were prepared with or without gluten and different powdered milk derivatives in the formulations. IBs were digested simulating an in vitro static gastrointestinal digestion for infants aged 6-12 months. BCMs and GEs were identified and quantified by UPLC/HR-MS. The amounts of BCM7 and the GE A5 were related to the beta-CN and gluten content of the formulations. To date, levels of BCMs and GEs in digests of IBs have not been reported in literature. This work represents an in vitro investigation regarding the release of opioid-acting peptides in IBs. It could add additional knowledge on complementary foods for infant health.File | Dimensione | Formato | |
---|---|---|---|
Pica_et_al(2021)_Infant_Biscuits_ShortCommunication_FoodChem_UncorrProofs.pdf
solo utenti autorizzati
Tipologia:
Post-print, accepted manuscript ecc. (versione accettata dall'editore)
Dimensione
737.41 kB
Formato
Adobe PDF
|
737.41 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
1-s2.0-S0308814621012681-main.pdf
solo utenti autorizzati
Tipologia:
Publisher's version/PDF
Dimensione
467.72 kB
Formato
Adobe PDF
|
467.72 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.