Analytical and clinical validation of a new immunoenzymatic method for the measurement of canine parathyroid hormone

Background: Renal hyperparathyroidism (RHPT) is frequent in dogs affected with Chronic Kidney Disease (CKD), with an increasing prevalence according to the severity of disease. The measurement of the parathyroid hormone (PTH) allows to establish adequate treatments, verify their effectiveness and follow the disease progression. However, due to lack of available methods and costs, it is not routinely performed. Objective: The aims of the study were: the analytical validation of a new immunoenzymatic method for the measurement of PTH validated in humans; the correlation of the obtained results with renal status, expressed as IRIS stage.