Introduction. Duration of untreated illness (DUI) has been increasingly investigated as a predictor of clinical outcome and course in different psychiatric disorders. To date, however, there are no tools for measuring this variable. Our group developed the Psychopathological Onset and Latency to Treatment Questionnaire (POLT-Q), focused on the onset of psychiatric disorders. Aim of this study was to assess the reproducibility and manageability of POLT-Q. Methods. Fifty consecutive in- and out-patients aged 16-65 with different DSM-5 psychiatric disorders were recruited. Two raters were present during the interview: one of them administered the POLT-Q to the patient and both independently completed the questionnaire. Collected values were compared using Cohen’s Kappa test and McNemar test. Results. 62.5% of the replies showed a 100% consistency between the two raters. In the 6.25% the agreement was <95%. For all the replies, the K coefficient was >0.8, a high degree of agreement. Discussion and conclusion. The POLT-Q assesses variables related to the psychopathological onset and first pharmacological treatment and, according to present findings, it represents a convenient, reliable and standardised measure for DUI. Further studies on larges sample are needed to confirm our preliminary results.
Introduzione. La durata di malattia non trattata (duration of untreated illness - DUI) è stata progressivamente studiata come predittore dell’andamento clinico e dell’outcome di malattia in diversi disturbi psichiatrici. A oggi, non esistono strumenti formali per misurare questa variabile. Il nostro gruppo di studio ha sviluppato il Questionario sull’esordio psicopatologico e la latenza al trattamento (Psychopathological Onset And Latency To Treatment Questionnaire - POLT-Q), che si focalizza sull’esordio dei disturbi psichiatrici. Lo scopo di questo lavoro consiste nella valutazione della riproducibilità e della maneggevolezza del POLT-Q. Metodi. Per il presente studio sono stati reclutati consecutivamente 50 pazienti, in regime di ricovero o ambulatoriale, di età compresa tra i 16 e i 65 anni e con diversi disturbi psichiatrici in accordo al DSM-5. Due valutatori erano presenti all’intervista clinica: mentre uno di questi somministrava il POLT-Q, entrambi compilavano il questionario indipendentemente. Le variabili così raccolte sono state confrontate utilizzando l’indice Kappa di Cohen e il test di McNemar. Risultati. Nel 62,5% delle risposte fornite i due valutatori hanno raggiunto una concordanza pari al 100%. Nel 6,25% delle risposte fornite, la concordanza è stata inferiore al 95%. Per tutte le risposte, il coefficiente K è risultato superiore a 0,8, corrispondente a un elevato livello di concordanza. Discussione e conclusioni. Il POLT-Q valuta le variabili relative all’esordio psicopatologico e al primo trattamento farmacologico e, secondo i risultati presentati nel corrente studio, rappresenta uno strumento conveniente, affidabile e standardizzato per misurare la DUI. Ulteriori studi su un campione più ampio potranno confermare i nostri risultati preliminari.
A new tool to assess duration of untreated illness: Psychopathological Onset and Latency to Treatment Questionnaire (POLT-Q) = Un nuovo strumento per valutare la durata di malattia non trattata: il questionario sull’esordio psicopatologico e la latenza al trattamento (POLT-Q) / L. Oldani, B. Benatti, V. De Carlo, I. Cortinovis, A.C. Altamura, B. Dell'Osso. - In: RIVISTA DI PSICHIATRIA. - ISSN 0035-6484. - 53:6(2018), pp. 290-298. [10.1708/3084.30762]
A new tool to assess duration of untreated illness: Psychopathological Onset and Latency to Treatment Questionnaire (POLT-Q) = Un nuovo strumento per valutare la durata di malattia non trattata: il questionario sull’esordio psicopatologico e la latenza al trattamento (POLT-Q)
L. Oldani
;B. Benatti;I. Cortinovis;A.C. Altamura;B. Dell'Osso
2018
Abstract
Introduction. Duration of untreated illness (DUI) has been increasingly investigated as a predictor of clinical outcome and course in different psychiatric disorders. To date, however, there are no tools for measuring this variable. Our group developed the Psychopathological Onset and Latency to Treatment Questionnaire (POLT-Q), focused on the onset of psychiatric disorders. Aim of this study was to assess the reproducibility and manageability of POLT-Q. Methods. Fifty consecutive in- and out-patients aged 16-65 with different DSM-5 psychiatric disorders were recruited. Two raters were present during the interview: one of them administered the POLT-Q to the patient and both independently completed the questionnaire. Collected values were compared using Cohen’s Kappa test and McNemar test. Results. 62.5% of the replies showed a 100% consistency between the two raters. In the 6.25% the agreement was <95%. For all the replies, the K coefficient was >0.8, a high degree of agreement. Discussion and conclusion. The POLT-Q assesses variables related to the psychopathological onset and first pharmacological treatment and, according to present findings, it represents a convenient, reliable and standardised measure for DUI. Further studies on larges sample are needed to confirm our preliminary results.File | Dimensione | Formato | |
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